Title:
METHOD FOR CATALYST-FREE PRODUCTION OF CYANOPHENOLS FROM METHOXYBENZONITRILES
Document Type and Number:
WIPO Patent Application WO2004026812
Kind Code:
A3
Abstract:
According to the inventive method for catalyst-free production of cyanophenols from methoxybenzonitriles, substituted methoxybenzonitriles of general formula (I) are reacted with an alkali alcoholate at temperatures of 80 - 230 DEG C. The inventive method is based on simple, low-cost and easily accessible raw materials and can be carried out in technically simple conditions, enabling cyanophenols to be produced with high and partially quantitative yields with guaranteed low waste levels. Sodium methanolate is used as a preferred alkali alcoholate at preferred temperatures of 140 - 180 DEG C. The methoxybenzonitrile component can optionally be produced by ammonoxidation of a methoxytoluol of ammonia and (air-)oxygen and be directly further reacted.
Inventors:
SANS JUERGEN (DE)
ERBEN HANS-GEORG (DE)
THALHAMMER FRANZ (DE)
GOMEZ ANDREU MARIO (DE)
ERBEN HANS-GEORG (DE)
THALHAMMER FRANZ (DE)
GOMEZ ANDREU MARIO (DE)
Application Number:
PCT/EP2003/009818
Publication Date:
May 13, 2004
Filing Date:
September 04, 2003
Export Citation:
Assignee:
DEGUSSA (DE)
SANS JUERGEN (DE)
ERBEN HANS-GEORG (DE)
THALHAMMER FRANZ (DE)
GOMEZ ANDREU MARIO (DE)
SANS JUERGEN (DE)
ERBEN HANS-GEORG (DE)
THALHAMMER FRANZ (DE)
GOMEZ ANDREU MARIO (DE)
International Classes:
C07C253/28; C07C255/53; C07C253/30; C07C255/54; (IPC1-7): C07C253/30; C07C255/53
Foreign References:
| US3567758A | 1971-03-02 | |||
| GB1065936A | 1967-04-19 | |||
| GB1442250A | 1976-07-14 |
Other References:
L. TESTAFERRI ET AL: "The reaction of unactivated aryl halides with sodium methoxide in HMPA", TETRAHEDRON, vol. 39, no. 1, 1983, pages 193 - 197, XP002274200
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