Title:
METHOD AND COMPOSITION FOR ANGIOGENESIS INHIBITION
Document Type and Number:
WIPO Patent Application WO2005079508
Kind Code:
A3
Abstract:
The invention features methods and compositions for inhibiting angiogenesis in a tissue or detecting angiogenesis using antagonists of denatured or proteolyzed forms of laminin.
Inventors:
FREIMARK BRUCE (US)
BROOKS PETER (US)
BROEK DANIEL (US)
BROOKS PETER (US)
BROEK DANIEL (US)
Application Number:
PCT/US2005/005322
Publication Date:
September 29, 2005
Filing Date:
February 17, 2005
Export Citation:
Assignee:
CANCERVAX CORP (US)
FREIMARK BRUCE (US)
BROOKS PETER (US)
BROEK DANIEL (US)
FREIMARK BRUCE (US)
BROOKS PETER (US)
BROEK DANIEL (US)
International Classes:
A61K38/04; A61K39/395; C07K16/00; C07K16/18; C07K16/28; (IPC1-7): C07K16/28; C07K16/00; A61K38/04; A61K39/395
Foreign References:
| US6620834B1 | 2003-09-16 | |||
| US5211657A | 1993-05-18 |
Other References:
KIKKAWA Y. ET AL: "Isolation and characterization of laminin-10/11 secreted by human lung carcinoma cells. laminin-10/11 mediates cell adhesion through integrin alpha3 beta1", J BIOL CHEM, vol. 273, no. 25, 19 June 1998 (1998-06-19), pages 15854 - 15859, XP002989633
ROUSSELLE P. ET AL: "Structural requirement for cell adhesion to kalinin (laminin-5)", J BIOL CHEM., vol. 270, no. 23, 9 June 1995 (1995-06-09), pages 13766 - 13770, XP002989634
GARGIA-LERMA J.G. ET AL: "Comparison of the anti-laminin antibody response in patients with systemic lupus erythematosus (SLE) and parasitic diseases (filariasis)", CLIN IMMUNOL IMMUNOPATHOL, vol. 76, no. 1, 1995, pages 19 - 31, XP002989635
ROUSSELLE P. ET AL: "Structural requirement for cell adhesion to kalinin (laminin-5)", J BIOL CHEM., vol. 270, no. 23, 9 June 1995 (1995-06-09), pages 13766 - 13770, XP002989634
GARGIA-LERMA J.G. ET AL: "Comparison of the anti-laminin antibody response in patients with systemic lupus erythematosus (SLE) and parasitic diseases (filariasis)", CLIN IMMUNOL IMMUNOPATHOL, vol. 76, no. 1, 1995, pages 19 - 31, XP002989635
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