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Title:
METHOD AND COMPOSITION FOR HAIR THICKENING
Document Type and Number:
WIPO Patent Application WO/2005/044205
Kind Code:
A1
Abstract:
It is intended to provide a method of keeping and accelerating hair thickening by promoting the expression of keratinocyte growth factor (FGF-7) in hair foliculus cells, preferably hair papilla cells; and a composition for promoting the expression of FGF-7 which contains adenosine and/or its derivative, in particular, an external agent for scalp aiming at keeping and accelerating hair thickening.

Inventors:
EHAMA RITSUKO (JP)
IINO MASATO (JP)
NAKAZAWA YOSUKE (JP)
TAJIMA MASAHIRO (JP)
OGOU MASASHI (JP)
ARASE SEIJI (JP)
Application Number:
PCT/JP2004/017037
Publication Date:
May 19, 2005
Filing Date:
November 10, 2004
Export Citation:
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Assignee:
SHISEIDO CO LTD (JP)
EHAMA RITSUKO (JP)
IINO MASATO (JP)
NAKAZAWA YOSUKE (JP)
TAJIMA MASAHIRO (JP)
OGOU MASASHI (JP)
ARASE SEIJI (JP)
International Classes:
A61K8/60; A61Q5/00; A61Q7/00; (IPC1-7): A61K7/06
Domestic Patent References:
WO2000047172A12000-08-17
Foreign References:
EP0998907A12000-05-10
DE4323616A11995-01-19
EP0387757A21990-09-19
JPH02311411A1990-12-27
JPS6442416A1989-02-14
JPH02204406A1990-08-14
JPS63101307A1988-05-06
JP2003155218A2003-05-27
JP2001288047A2001-10-16
JP2001288046A2001-10-16
JP2001288043A2001-10-16
JP2001288042A2001-10-16
JP2001288045A2001-10-16
JP2001288048A2001-10-16
Other References:
SUN, L.L. ET AL.: "Cyclopentyladenosine improves cell proliferation, wound healing, and hair growth", JOURNAL OF SURGICAL RESEARCH, vol. 87, no. 1, 1999, pages 14 - 24, XP002928512
PIERCE, G.F. ET AL.: "Stimulation of all epithelial elements during skin regeneration by keratinocyte growth factor", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 179, no. 3, 1994, pages 831 - 840, XP001117667
ROSENQUIST, T.A. ET AL.: "Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle", DEVELOPMENTAL DYNAMICS: AN OFFICIAL PUBLICATION OF THE AMERICAN ASSOCIATION OF ANATOMISTS, vol. 205, no. 4, 1996, pages 379 - 386, XP002984440
See also references of EP 1683509A4
Attorney, Agent or Firm:
Aoki, Atsushi (ISHIDA & ASSOCIATES Toranomon 37 Mori Bldg., 5-, Toranomon 3-chome Minato-ku Tokyo 23, JP)
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