Title:
METHOD FOR CONSTRUCTING ONCOLYTIC VIRUS
Document Type and Number:
WIPO Patent Application WO/2022/033467
Kind Code:
A1
Abstract:
Provided is a method for constructing an oncolytic virus. The method comprises the following steps: a. determining a tumor cell specific receptor; b. determining a target virus ligand on the basis of binding forces between virus ligands and the tumor cell specific receptor; and c. constructing an oncolytic virus comprising the target virus ligand.
Inventors:
WU KEXING (CN)
Application Number:
PCT/CN2021/111759
Publication Date:
February 17, 2022
Filing Date:
August 10, 2021
Export Citation:
Assignee:
REVOIMMUNE THERAPEUTICS INC (CN)
International Classes:
A61K35/76; A61P35/00; C12N15/64
Foreign References:
| US20130295114A1 | 2013-11-07 | |||
| US20160317591A1 | 2016-11-03 | |||
| US20180085411A1 | 2018-03-29 | |||
| CN102191224A | 2011-09-21 | |||
| CN110325207A | 2019-10-11 |
Other References:
JAYAWARDENA NADISHKA, POIRIER JOHN T, BURGA LAURA N, BOSTINA MIHNEA: "Virus–Receptor Interactions and Virus Neutralization: Insights for Oncolytic Virus Development", ONCOLYTIC VIROTHERAPY, vol. Volume 9, 6 March 2020 (2020-03-06), pages 1 - 15, XP055900268, DOI: 10.2147/OV.S186337
Attorney, Agent or Firm:
TSINGYIHUA INTELLECTUAL PROPERTY LLC (CN)
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