METHOD FOR CULTURE OF LACTIC ACID BACTERIUM HAVING HIGH IMMUNOMODULATING ACTIVITY

Title:

METHOD FOR CULTURE OF LACTIC ACID BACTERIUM HAVING HIGH IMMUNOMODULATING ACTIVITY

Document Type and Number:

WIPO Patent Application WO/2007/138993

Kind Code:

A1

Abstract:

A study is intensively made about the influence of the culture conditions for a lactic acid bacterium on the activity of promoting the production of IL-12 from a murine splenic cell. The study reveals that the pH value of a culture medium is a factor which is largely involved in the activity of modulating the immunological functions of the lactic acid bacterium.

Inventors:

SASHIHARA TOSHIHIRO (JP)
FURUICHI KEISUKE (JP)

Application Number:

PCT/JP2007/060665

Publication Date:

December 06, 2007

Filing Date:

May 25, 2007

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MEIJI DAIRIES CORP (JP)
SASHIHARA TOSHIHIRO (JP)
FURUICHI KEISUKE (JP)

International Classes:

C12N1/20; A23L1/28; A23L1/30; A23L33/00; A23L33/10; A23L33/135; A61K35/74; A61K35/744; A61K35/747; A61P11/06; A61P17/00; A61P27/16; A61P37/02; A61P37/08; A61P43/00

Domestic Patent References:

WO2001090311A1	2001-11-29
WO1999029833A1	1999-06-17
WO2002050311A2	2002-06-27
WO2004003235A2	2004-01-08
WO2006093022A1	2006-09-08

Foreign References:

JP2005139160A

2005-06-02

Other References:

KA H.: "Allergy no Rinsho ni Yoseru -465- Probiotics Nyusankin Lactobacillus gasseri TMC0356 Kabu no Men'eki Shushoku Oyobi Ko Allergy Sayo", ALLERGY NO RINSHO, no. 338, 2005, pages 983 - 988, XP003019813
SASHIHARA N.: "Lactobacillus Gasseri OLL2809 no Baiyo Joken ga Men'eki Chosetsu Kassei ni Oyobosu Eikyo no Kento (Effect of growth conditions of Lactobacillus gasseri OLL2809 on stimulatory activity for IL-12 production by murine splenocytes)", JOURNAL OF JAPAN SOCIETY FOR LACTIC ACID BACTERIA, vol. 17, no. 1, 1 June 2006 (2006-06-01), pages 82, XP003019814