Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR DETECTING FOOD-NOXIOUS SUBSTANCE
Document Type and Number:
WIPO Patent Application WO/2023/033582
Kind Code:
A1
Abstract:
The present invention relates to a method for detecting a food-noxious substance and, more specifically, to a method for detecting a food-noxious substance wherein, with selective molecular affinity, a food-noxious substance-specific aptamer is bound to a capture probe fixed to a chip in the absence of the food-noxious substance, but departs from the capture probe and binds to the food noxious substance in the presence of the food-noxious substance, so that a circular DNA binds to the capture probe and undergoes an RCA reaction to form a metal body for signal amplification, whereby detection accuracy can be improved.

Inventors:
WOO MIN AH (KR)
CHOI SUNG WOOK (KR)
LIM MIN CHEOL (KR)
CHANG HYUN JOO (KR)
KIM TAI YONG (KR)
Application Number:
PCT/KR2022/013171
Publication Date:
March 09, 2023
Filing Date:
September 02, 2022
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KOREA FOOD RES INST (KR)
International Classes:
C12Q1/6834
Foreign References:
KR20150044397A2015-04-24
KR101050421B12011-07-19
KR20190096030A2019-08-19
KR20220031527A2022-03-11
Other References:
LIU XIAOJUAN, SONG MENGMENG, HOU TING, LI FENG: "Label-Free Homogeneous Electroanalytical Platform for Pesticide Detection Based on Acetylcholinesterase-Mediated DNA Conformational Switch Integrated with Rolling Circle Amplification", ACS SENSORS, AMERICAN CHEMICAL SOCIETY, US, vol. 2, no. 4, 28 April 2017 (2017-04-28), US, pages 562 - 568, XP093043547, ISSN: 2379-3694, DOI: 10.1021/acssensors.7b00081
KIM, TAI-YONG ET AL.: "Rolling circle amplification-based copper nanoparticle synthesis on cyclic olefin copolymer substrate and its application in aptasensor", BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, vol. 27, no. 2, 22 April 2022 (2022-04-22), pages 202 - 212, XP037816252, DOI: 10.1007/s12257-021-0220-0
Attorney, Agent or Firm:
KIM, Hyun Jin (KR)
Download PDF: