Title:
METHOD FOR DETECTING FOOD-NOXIOUS SUBSTANCE
Document Type and Number:
WIPO Patent Application WO/2023/033582
Kind Code:
A1
Abstract:
The present invention relates to a method for detecting a food-noxious substance and, more specifically, to a method for detecting a food-noxious substance wherein, with selective molecular affinity, a food-noxious substance-specific aptamer is bound to a capture probe fixed to a chip in the absence of the food-noxious substance, but departs from the capture probe and binds to the food noxious substance in the presence of the food-noxious substance, so that a circular DNA binds to the capture probe and undergoes an RCA reaction to form a metal body for signal amplification, whereby detection accuracy can be improved.
Inventors:
WOO MIN AH (KR)
CHOI SUNG WOOK (KR)
LIM MIN CHEOL (KR)
CHANG HYUN JOO (KR)
KIM TAI YONG (KR)
CHOI SUNG WOOK (KR)
LIM MIN CHEOL (KR)
CHANG HYUN JOO (KR)
KIM TAI YONG (KR)
Application Number:
PCT/KR2022/013171
Publication Date:
March 09, 2023
Filing Date:
September 02, 2022
Export Citation:
Assignee:
KOREA FOOD RES INST (KR)
International Classes:
C12Q1/6834
Foreign References:
KR20150044397A | 2015-04-24 | |||
KR101050421B1 | 2011-07-19 | |||
KR20190096030A | 2019-08-19 | |||
KR20220031527A | 2022-03-11 |
Other References:
LIU XIAOJUAN, SONG MENGMENG, HOU TING, LI FENG: "Label-Free Homogeneous Electroanalytical Platform for Pesticide Detection Based on Acetylcholinesterase-Mediated DNA Conformational Switch Integrated with Rolling Circle Amplification", ACS SENSORS, AMERICAN CHEMICAL SOCIETY, US, vol. 2, no. 4, 28 April 2017 (2017-04-28), US, pages 562 - 568, XP093043547, ISSN: 2379-3694, DOI: 10.1021/acssensors.7b00081
KIM, TAI-YONG ET AL.: "Rolling circle amplification-based copper nanoparticle synthesis on cyclic olefin copolymer substrate and its application in aptasensor", BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, vol. 27, no. 2, 22 April 2022 (2022-04-22), pages 202 - 212, XP037816252, DOI: 10.1007/s12257-021-0220-0
KIM, TAI-YONG ET AL.: "Rolling circle amplification-based copper nanoparticle synthesis on cyclic olefin copolymer substrate and its application in aptasensor", BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, vol. 27, no. 2, 22 April 2022 (2022-04-22), pages 202 - 212, XP037816252, DOI: 10.1007/s12257-021-0220-0
Attorney, Agent or Firm:
KIM, Hyun Jin (KR)
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