Title:
METHOD FOR DETECTING HEPARIN OR HEPARIN-LIKE SUBSTANCES IN BLOOD AND KIT
Document Type and Number:
WIPO Patent Application WO/2021/000654
Kind Code:
A1
Abstract:
A method for detecting heparin or heparin-like substances in blood, comprising: dividing a same blood sample to two parts having the equal mass, and recording same as a first blood sample and a second blood sample; mixing the first blood sample with a heparin neutralizing agent to obtain a mixture; performing detection of a first coagulation time after the mixture and a first coagulant are mixed to obtain a first coagulation time; and performing detection of a second coagulation time after the second blood sample and a second coagulant are mixed to obtain a second coagulation time; wherein the first coagulant and the second coagulant have the same composition and the same use amount; the first coagulation time and the second coagulation time have the same detection method; and if a time difference between the first coagulation time and the second coagulation time is greater than 5 seconds, the blood sample contains heparin or heparin-like substances. The detection costs of the detection method are reduced, and the method is easy to operate and suitable for clinical promotion.
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Inventors:
LI GANG (CN)
Application Number:
PCT/CN2020/090322
Publication Date:
January 07, 2021
Filing Date:
May 14, 2020
Export Citation:
Assignee:
ZIRCON BIOTECH CO LTD (CN)
International Classes:
G01N33/49
Foreign References:
| CN110208513A | 2019-09-06 | |||
| US20140038205A1 | 2014-02-06 | |||
| CN109709292A | 2019-05-03 | |||
| CN102141570A | 2011-08-03 | |||
| CN108982865A | 2018-12-11 | |||
| CN107561257A | 2018-01-09 | |||
| CN107091814A | 2017-08-25 |
Other References:
GOODMAN ET AL: "The Pharmacological Basis of Therapeutics", THE PHARMACOLOGICAL BASIS OF THERAPEUTICS, 31 March 1963 (1963-03-31), pages 987 - 988, XP009525399
Attorney, Agent or Firm:
ZHONG LUN LAW FIRM (CN)
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