Title:
METHOD FOR DETECTING AND MEASURING TARGET SUBSTANCE ON BASIS OF MEASUREMENT OF POLARIZATION ANISOTROPY, AND PARTICLES USED THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/259946
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a method and a kit for measuring a target substance having high detection sensitivity. Provided is a method for measuring at least one among the presence or absence and the concentration of a target substance in a sample solution, the method comprising: (a) a step for preparing first particles which specifically bind to the target substance and contain a rare earth complex, and second particles which have a larger average particle diameter than the first particles and specifically bind to the target substance; (b) a step for mixing the sample solution, the first particles, and the second particles to obtain a mixed solution; and (c) a step for determining at least one among the presence or absence and the concentration of the target substance from the polarization anisotropy of the mixed solution obtained in (b).
Inventors:
KAKEGAWA NORISHIGE (JP)
MASUMURA TAKAHIRO (JP)
SAKAKIBARA TEIGO (JP)
NAKAJIMA IKUO (JP)
YAMAUCHI FUMIO (JP)
KANAZAKI KENGO (JP)
MASUMURA TAKAHIRO (JP)
SAKAKIBARA TEIGO (JP)
NAKAJIMA IKUO (JP)
YAMAUCHI FUMIO (JP)
KANAZAKI KENGO (JP)
Application Number:
PCT/JP2022/022413
Publication Date:
December 15, 2022
Filing Date:
June 02, 2022
Export Citation:
Assignee:
CANON KK (JP)
CANON MEDICAL SYSTEMS CORP (JP)
CANON MEDICAL SYSTEMS CORP (JP)
International Classes:
G01N21/64; G01N33/543
Domestic Patent References:
WO2019132045A1 | 2019-07-04 | |||
WO2019208711A1 | 2019-10-31 |
Foreign References:
JPH0772155A | 1995-03-17 | |||
JP2000146975A | 2000-05-26 | |||
JP2893772B2 | 1999-05-24 | |||
JPH10512751A | 1998-12-08 | |||
US20110207614A1 | 2011-08-25 | |||
JPH0352575B2 | 1991-08-12 | |||
JP2893772B2 | 1999-05-24 | |||
JPH03103765A | 1991-04-30 | |||
JP2021096211A | 2021-06-24 |
Attorney, Agent or Firm:
OKABE Yuzuru et al. (JP)
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