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Title:
METHOD FOR DETECTING AND MEASURING TARGET SUBSTANCE ON BASIS OF MEASUREMENT OF POLARIZATION ANISOTROPY, AND PARTICLES USED THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/259946
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a method and a kit for measuring a target substance having high detection sensitivity. Provided is a method for measuring at least one among the presence or absence and the concentration of a target substance in a sample solution, the method comprising: (a) a step for preparing first particles which specifically bind to the target substance and contain a rare earth complex, and second particles which have a larger average particle diameter than the first particles and specifically bind to the target substance; (b) a step for mixing the sample solution, the first particles, and the second particles to obtain a mixed solution; and (c) a step for determining at least one among the presence or absence and the concentration of the target substance from the polarization anisotropy of the mixed solution obtained in (b).

Inventors:
KAKEGAWA NORISHIGE (JP)
MASUMURA TAKAHIRO (JP)
SAKAKIBARA TEIGO (JP)
NAKAJIMA IKUO (JP)
YAMAUCHI FUMIO (JP)
KANAZAKI KENGO (JP)
Application Number:
PCT/JP2022/022413
Publication Date:
December 15, 2022
Filing Date:
June 02, 2022
Export Citation:
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Assignee:
CANON KK (JP)
CANON MEDICAL SYSTEMS CORP (JP)
International Classes:
G01N21/64; G01N33/543
Domestic Patent References:
WO2019132045A12019-07-04
WO2019208711A12019-10-31
Foreign References:
JPH0772155A1995-03-17
JP2000146975A2000-05-26
JP2893772B21999-05-24
JPH10512751A1998-12-08
US20110207614A12011-08-25
JPH0352575B21991-08-12
JP2893772B21999-05-24
JPH03103765A1991-04-30
JP2021096211A2021-06-24
Attorney, Agent or Firm:
OKABE Yuzuru et al. (JP)
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