Title:
METHOD FOR DETECTING METHYLATION OF SDC2 GENE
Document Type and Number:
WIPO Patent Application WO/2020/256293
Kind Code:
A1
Abstract:
The present invention relates to a method for detecting methylation of an SDC2 gene, a composition for detecting methylation of an SDC2 gene, and a kit comprising same and, more specifically, to: a method for detecting methylation of an SDC2 gene by using primers for specifically amplifying a methylated SDC2 gene and a probe capable of complementarily hybridizing with a methylated SDC2 gene that has been specifically amplified by the primers; a composition for detecting methylation of an SDC2 gene; and a kit comprising same.
Inventors:
AN SUNGHWAN (KR)
OH TAE JEONG (KR)
OH TAE JEONG (KR)
Application Number:
PCT/KR2020/006692
Publication Date:
December 24, 2020
Filing Date:
May 22, 2020
Export Citation:
Assignee:
GENOMICTREE INC (KR)
International Classes:
C12Q1/6876; C12Q1/6813
Domestic Patent References:
| WO2018194280A1 | 2018-10-25 |
Foreign References:
| KR20150114844A | 2015-10-13 | |||
| KR20110084487A | 2011-07-25 | |||
| KR101142131B1 | 2012-05-11 |
Other References:
"Hints for optimizing bisulfite primer design", 12 September 2014 (2014-09-12), XP055560236, Retrieved from the Internet
H�L�NE THOMASSIN, CL�MENCE KRESS, AND THIERRY GRANGE: "MethylQuant: a sensitive method for quantifying methylation of specific cytosines within the genome.", NUCLEIC ACIDS RESEARCH, INFORMATION RETRIEVAL LTD., GB, vol. 32, no. 21, 1 January 2004 (2004-01-01), GB, pages E168 - E168-9, XP002691673, ISSN: 0305-1048, DOI: 10.1093/NAR/GNH166
CROSS, S ET AL., CURR. OPIN. GENE DEVELOP., vol. 5, 1995, pages 309
AHLQUIST, D.A. ET AL., GASTROENTEROL, vol. 119, 2000, pages 1219
See also references of EP 3992306A4
H�L�NE THOMASSIN, CL�MENCE KRESS, AND THIERRY GRANGE: "MethylQuant: a sensitive method for quantifying methylation of specific cytosines within the genome.", NUCLEIC ACIDS RESEARCH, INFORMATION RETRIEVAL LTD., GB, vol. 32, no. 21, 1 January 2004 (2004-01-01), GB, pages E168 - E168-9, XP002691673, ISSN: 0305-1048, DOI: 10.1093/NAR/GNH166
CROSS, S ET AL., CURR. OPIN. GENE DEVELOP., vol. 5, 1995, pages 309
AHLQUIST, D.A. ET AL., GASTROENTEROL, vol. 119, 2000, pages 1219
See also references of EP 3992306A4
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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