Title:
METHOD FOR DETECTING MONOSACCHARIDE AND OLIGOSACCHARIDE CONTENT AND FINGERPRINT SPECTURM OF COMPOUND SOPHORA FLAVESCENS INJECTION
Document Type and Number:
WIPO Patent Application WO/2022/116972
Kind Code:
A1
Abstract:
A method for detecting the monosaccharide and oligosaccharide content and fingerprint spectrum of a compound sophora flavescens injection, comprising: carrying out detection by using a high-performance liquid chromatography-evaporation light scattering detection method, wherein the monosaccharides and oligosaccharides are D-anhydrous glucose, D-fructose, sucrose and pinitol. Th present method is an improved method for detecting monosaccharides and oligosaccharides of a compound sophora flavescens injection, and can measure four saccharide components in the compound sophora flavescens injection at the same time, and constructs an HPLC-ELSD fingerprint spectrum to provide a technical method for the quality control of the saccharide components in the compound sophora flavescens injection.
Inventors:
DUAN XIUMEI (CN)
HAI LINA (CN)
WANG HONGLING (CN)
QIN WENJIE (CN)
WANG HONGYU (CN)
HAI LINA (CN)
WANG HONGLING (CN)
QIN WENJIE (CN)
WANG HONGYU (CN)
Application Number:
PCT/CN2021/134502
Publication Date:
June 09, 2022
Filing Date:
November 30, 2021
Export Citation:
Assignee:
BEIJING ZHENDONG GUANGMING PHARMACEUTICAL RES INSTITUTE CO LTD (CN)
International Classes:
G01N30/36; G01N30/02; G01N30/26
Foreign References:
| CN110862305A | 2020-03-06 | |||
| CN103543222A | 2014-01-29 | |||
| CN102384896A | 2012-03-21 | |||
| CN101776654A | 2010-07-14 | |||
| KR20100122222A | 2010-11-22 | |||
| CN109001316A | 2018-12-14 |
Other References:
LI, BOWEN ET AL.: "Determination of Pinitol in Fufang Kushen Injection by HPLC-ELSD", CHINESE JOURNAL OF INFORMATION ON TRADITIONAL CHINESE MEDICINE, vol. 21, no. 2, 15 February 2014 (2014-02-15), pages 83 - 85, XP055937810
Attorney, Agent or Firm:
BEIJING LONGAN LAW FIRM (CN)
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