Title:
METHOD OF DETECTING RHABDOMYOSARCOMA USING SAMPLE DERIVED FROM BODY FLUID
Document Type and Number:
WIPO Patent Application WO/2011/126089
Kind Code:
A1
Abstract:
Provided is a method of detecting rhabdomyosarcoma, whereby the expression of at least one type of miRNA selected from a group comprising hsa-miR-1, hsa-miR-133a, hsa-miR-133b and hsa-miR-206 in a sample derived from body fluid is evaluated.
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Inventors:
HOSOI HAJIME (JP)
MIYACHI MITSURU (JP)
MIYACHI MITSURU (JP)
Application Number:
PCT/JP2011/058843
Publication Date:
October 13, 2011
Filing Date:
April 07, 2011
Export Citation:
Assignee:
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
HOSOI HAJIME (JP)
MIYACHI MITSURU (JP)
HOSOI HAJIME (JP)
MIYACHI MITSURU (JP)
International Classes:
C12N15/113; C12Q1/68; G01N33/50
Domestic Patent References:
| WO2008117278A2 | 2008-10-02 |
Other References:
YAN D. ET AL.: "MicroRNA-1/206 Targets c-Met and Inhibits Rhabdomyosarcoma Development", J. BIOL. CHEM., vol. 284, no. 43, 2009, pages 29596 - 29604, XP008161726
MCCARTHY JJ. ET AL.: "MicroRNA-206: the skeletal muscle-specific myomiR", BIOCHIM. BIOPHYS. ACTA, vol. 1779, no. 11, 2008, pages 682 - 691, XP025678668
MITSURU MIYACHI ET AL.: "Kesseichu Kintokuiteki microRNA miR-206 wa Omonkinnikushu no Shinki Kessei Shuyo Marker de aru", THE JAPANESE SOCIETY OF PEDIATRIC HEMATOLOGY, JAPANESE SOCIETY OF PEDIATRIC ONCOLOGY, JAPANESE SOCIETY OF PEDIATRIC ONCOLOGY NURSING, vol. 52ND-26T, November 2010 (2010-11-01), pages 194, XP008161694
MIYACHI M. ET AL.: "Circulating muscle-specific microRNA, miR-206, as a potential diagnostic marker for rhabdomyosarcoma", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 400, no. 1, August 2010 (2010-08-01), pages 89 - 93, XP027275786
GOTOH ET AL., J CLIN ONCOL, vol. 23, 2005, pages 5205 - 5210
YAGYU ET AL., CLIN CANCER RES, vol. 14, 2008, pages 7011 - 7019
CALIN GA ET AL., NAT REV CANCER, vol. 6, 2006, pages 857 - 866
LU J ET AL., NATURE, vol. 435, 2005, pages 834 - 838
WEI JS ET AL., CLIN CANCER RES, vol. 15, 2009, pages 5560 - 5568
SUBRAMANIAN S ET AL., ONCOGENE, vol. 27, 2008, pages 2015 - 2026
NG EKO ET AL., GUT, vol. 58, 2009, pages 1375 - 1381
MITCHELL PS ET AL., PNAS, vol. 105, 2008, pages 10513 - 10518
LAWRIE CH ET AL., BR J HAEMATOL, vol. 141, 2008, pages 672 - 675
YAMAMOTO Y ET AL., BIOMARKERS, vol. 14, 2009, pages 529 - 538
See also references of EP 2557162A4
MCCARTHY JJ. ET AL.: "MicroRNA-206: the skeletal muscle-specific myomiR", BIOCHIM. BIOPHYS. ACTA, vol. 1779, no. 11, 2008, pages 682 - 691, XP025678668
MITSURU MIYACHI ET AL.: "Kesseichu Kintokuiteki microRNA miR-206 wa Omonkinnikushu no Shinki Kessei Shuyo Marker de aru", THE JAPANESE SOCIETY OF PEDIATRIC HEMATOLOGY, JAPANESE SOCIETY OF PEDIATRIC ONCOLOGY, JAPANESE SOCIETY OF PEDIATRIC ONCOLOGY NURSING, vol. 52ND-26T, November 2010 (2010-11-01), pages 194, XP008161694
MIYACHI M. ET AL.: "Circulating muscle-specific microRNA, miR-206, as a potential diagnostic marker for rhabdomyosarcoma", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 400, no. 1, August 2010 (2010-08-01), pages 89 - 93, XP027275786
GOTOH ET AL., J CLIN ONCOL, vol. 23, 2005, pages 5205 - 5210
YAGYU ET AL., CLIN CANCER RES, vol. 14, 2008, pages 7011 - 7019
CALIN GA ET AL., NAT REV CANCER, vol. 6, 2006, pages 857 - 866
LU J ET AL., NATURE, vol. 435, 2005, pages 834 - 838
WEI JS ET AL., CLIN CANCER RES, vol. 15, 2009, pages 5560 - 5568
SUBRAMANIAN S ET AL., ONCOGENE, vol. 27, 2008, pages 2015 - 2026
NG EKO ET AL., GUT, vol. 58, 2009, pages 1375 - 1381
MITCHELL PS ET AL., PNAS, vol. 105, 2008, pages 10513 - 10518
LAWRIE CH ET AL., BR J HAEMATOL, vol. 141, 2008, pages 672 - 675
YAMAMOTO Y ET AL., BIOMARKERS, vol. 14, 2009, pages 529 - 538
See also references of EP 2557162A4
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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