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Title:
METHOD FOR DETECTING TARGET BIOMOLECULE IN BIOLOGICAL SAMPLE, DISPOSABLE OPTICAL FIBER SENSOR THEREFOR, AND CARTRIDGE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/045757
Kind Code:
A1
Abstract:
Disclosed are: a method for detecting a target biomolecule in a biological sample, in which the method can be rapidly and inexpensively performed on site to diagnose diseases such as infectious diseases; an FO-LSPR optical fiber sensor which can be used therein; and a disposable sensor cartridge having the sensor mounted. The disposal sensor cartridge of the present invention can be used in the rapid detection of a target biomolecule, by mounting an optical fiber sensor and then connecting FO-LSPR equipment thereto. When an FO-LSPR molecular diagnostic system using the optical fiber sensor cartridge of the present invention is combined with a CRISPR-Cas system, target biomolecules can be detected accurately and conveniently without nucleic acid amplification.

Inventors:
HAN BYOUNG DON (KR)
CHOI YOUNG CHUL (KR)
CHOI HEE BAEG (KR)
LEE HAE JIN (KR)
HWANG KUN TAHK (KR)
Application Number:
PCT/KR2021/011345
Publication Date:
March 03, 2022
Filing Date:
August 25, 2021
Export Citation:
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Assignee:
MBT CO LTD (KR)
International Classes:
G01N21/552; C12N9/22; C12N15/10; C12Q1/6806; C12Q1/70; G01N1/10; G01N1/36; G01N21/59; G01N21/64; G01N33/48
Domestic Patent References:
WO2019104058A12019-05-31
Foreign References:
US20170298426A12017-10-19
US20110150705A12011-06-23
KR101035230B12011-05-18
Other References:
TSOU JEN-HUI, QIXIN LENG, FENG JIANG: "A CRISPR test for detection of circulating nuclei acids", TRANSLATIONAL ONCOLOGY, vol. 12, no. 12, 31 December 2019 (2019-12-31), pages 1566 - 1573, XP055904233, DOI: 10.1016/j.tranon.2019.08.011
Attorney, Agent or Firm:
AJU INTERNATIONAL LAW & PATENT GROUP (KR)
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