Title:
METHOD FOR DETERMINING SENSITIVITY TO SIDE EFFECTS OF RETINOIDS
Document Type and Number:
WIPO Patent Application WO/2019/044852
Kind Code:
A1
Abstract:
Provided are a method for determining a subject's sensitivity to the side effects of retinoids on the basis of genetic elements by SNP analysis, a computer that determines sensitivity to the side effects of retinoids, and a program that controls the computer. There is a demand for the development of methods of mitigating sensitivity, beauty instruction services, and the development of cosmetic selection methods on the basis of a subject's determined sensitivity to the side effects of retinoids. Sensitivity to the side effects of retinoids can be determined on the basis of the detection of at least one SNP selected from the group consisting of the following: rs117761959、rs35515429、rs35736558、rs61840347、rs12754142、rs9290978、rs28501222、rs117675886、rs117758125、rs875705、rs58310152、rs58286474、rs112273273、rs73380909、rs73380910、rs73380913、rs12655922、rs17068781、rs278015、rs17068796、rs73381002、rs59490468、rs117142738、rs10086126、rs145653129、rs1903895、rs2574810、rs6480852、rs497578、rs562187、rs531402、rs2574801、rs2247887、rs2247880、rs814014、rs137908383、rs186198501、rs7933887、rs80067170、rs78606856、rs12100559、rs150171951、rs2060609、rs2060608、rs1349250、rs145745344、rs57595200、rs8008945、rs12907778、rs151092710、rs28363677、rs16948876、rs17753299、rs150302670, and rs763038.
Inventors:
AMANO SATOSHI (JP)
IDETA RITSURO (JP)
OTA MASAHIRO (JP)
NOMURA YOSHIFUMI (JP)
OCHIAI MISAKI (JP)
KAMINUMA MIKIKO (JP)
IDETA RITSURO (JP)
OTA MASAHIRO (JP)
NOMURA YOSHIFUMI (JP)
OCHIAI MISAKI (JP)
KAMINUMA MIKIKO (JP)
Application Number:
PCT/JP2018/031823
Publication Date:
March 07, 2019
Filing Date:
August 28, 2018
Export Citation:
Assignee:
SHISEIDO CO LTD (JP)
International Classes:
C12Q1/6827; C12N15/09; C12Q1/6876
Foreign References:
| JP2013189397A | 2013-09-26 | |||
| US20090197953A1 | 2009-08-06 | |||
| JP2014524735A | 2014-09-25 |
Other References:
ALZOUBI, KAREM H. ET AL.: "The effect of genetic polymorphisms of RARA gene on the adverse effects profile of isotretinoin-treated acne patients", INT. J. CLIN. PHARMACOL. THER., vol. 51, no. 8, 2013, pages 631 - 640
WU, YING ET AL.: "TRPV1 channels are functionally coupled with BK(mSlol) channels in rat dorsal root ganglion (DRG) neurons", PLOS ONE, vol. 8, no. 10, 16 October 2013 (2013-10-16), pages e78203, XP055581005
WU, YING ET AL.: "TRPV1 channels are functionally coupled with BK(mSlol) channels in rat dorsal root ganglion (DRG) neurons", PLOS ONE, vol. 8, no. 10, 16 October 2013 (2013-10-16), pages e78203, XP055581005
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
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