Title:
METHOD FOR DETERMINING SYNUCLEINOPATHY
Document Type and Number:
WIPO Patent Application WO/2024/005008
Kind Code:
A1
Abstract:
The present disclosure provides a method for determining whether or not a subject is suffering from synucleinopathy on the basis of a level of ApoA1 that is bonded to α-synuclein in a sample which has been taken from the subject.
Inventors:
MACHIDA KIYOTAKA (JP)
YABUSHITA HISATOSHI (JP)
NOSE KAZUTOSHI (JP)
YABUSHITA HISATOSHI (JP)
NOSE KAZUTOSHI (JP)
Application Number:
PCT/JP2023/023779
Publication Date:
January 04, 2024
Filing Date:
June 27, 2023
Export Citation:
Assignee:
OTSUKA PHARMA CO LTD (JP)
International Classes:
G01N33/68; C07K1/14; C12Q1/00
Domestic Patent References:
| WO2021094751A1 | 2021-05-20 |
Foreign References:
| JP2016524151A | 2016-08-12 | |||
| JP2019523758A | 2019-08-29 | |||
| JP2020511662A | 2020-04-16 | |||
| JP2017193571A | 2017-10-26 | |||
| US20180238902A1 | 2018-08-23 | |||
| US20190085394A1 | 2019-03-21 |
Other References:
SCHAPIRA ANTHONY: "Recent developments in biomarkers in Parkinson disease", CURRENT OPINION IN NEUROLOGY, vol. 26, no. 4, 1 August 2013 (2013-08-01), pages 395 - 400, XP009551505
EMAMZADEH FATEMEH NOURI: "Role of Apolipoproteins and α-Synuclein in Parkinson’s Disease", JOURNAL OF MOLECULAR NEUROSCIENCE, BIRKHAEUSER, CAMBRIDGE, MA., US, vol. 62, no. 3, 10 July 2017 (2017-07-10), US , pages 344 - 355, XP036290581, ISSN: 0895-8696, DOI: 10.1007/s12031-017-0942-9
EMAMZADEH FATEMEH NOURI: "Role of Apolipoproteins and α-Synuclein in Parkinson’s Disease", JOURNAL OF MOLECULAR NEUROSCIENCE, BIRKHAEUSER, CAMBRIDGE, MA., US, vol. 62, no. 3, 10 July 2017 (2017-07-10), US , pages 344 - 355, XP036290581, ISSN: 0895-8696, DOI: 10.1007/s12031-017-0942-9
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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