Title:
METHOD FOR DETERMINING THE VOLUME OF DISTRIBUTION OF A BLOOD COMPONENT DURING A BLOOD TREATMENT, AND DEVICE
Document Type and Number:
WIPO Patent Application WO2000038761
Kind Code:
A3
Abstract:
The invention relates to a method for determining the volume of distribution of a blood component in the body of a living organism, especially the volume of distribution of urea, during an extracorporeal blood treatment. According to this method, the blood to be treated flows through the blood chamber (3) of a dialysis machine (1) in an extracorporeal circuit, said dialysis machine being divided into said blood chamber and a dialysing liquid chamber (4) by a semipermeable membrane (2). Dialysing liquid flows through the dialysing liquid chamber of the dialysis machine in a dialysing liquid channel. The method is based on the determination of the temporal change in the concentration of the blood component in the blood upstream of the dialysis machine using the temporal variation in a physical or chemical characteristic of the dialysing liquid upstream and downstream of the dialysis machine and the determination of the volume of distribution of the substance in the body of a living organism using the temporal variation in the concentration of the blood component in the blood. The invention also relates to a device for the extracorporeal blood treatment, comprising a device for determining the volume of distribution of a blood component in the body of a living organism.
Inventors:
GOLDAU RAINER (DE)
GRAF THOMAS (DE)
GROSS MALTE (DE)
GRAF THOMAS (DE)
GROSS MALTE (DE)
Application Number:
PCT/EP1999/010338
Publication Date:
October 11, 2001
Filing Date:
December 23, 1999
Export Citation:
Assignee:
FRESENIUS MEDICAL CARE DE GMBH (DE)
GOLDAU RAINER (DE)
GRAF THOMAS (DE)
GROSS MALTE (DE)
GOLDAU RAINER (DE)
GRAF THOMAS (DE)
GROSS MALTE (DE)
International Classes:
A61B5/145; A61B5/1459; A61B5/1473; A61M1/14; A61M1/16; (IPC1-7): A61M1/16
Domestic Patent References:
| WO1998055166A1 | 1998-12-10 | |||
| WO1999029355A1 | 1999-06-17 |
Foreign References:
| EP0291421A1 | 1988-11-17 | |||
| EP0330892A2 | 1989-09-06 | |||
| US4267040A | 1981-05-12 | |||
| DE3938662A1 | 1991-07-18 |
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