Title:
METHOD AND DEVICE FOR CONTROLLING CRYSTAL GROWTH
Document Type and Number:
WIPO Patent Application WO2001088231
Kind Code:
A3
Abstract:
The present invention provides novel devices and method for kinetically controlling vapor diffusion in crystal growth. The devices comprise discrete diffusion pathways which control the kinetics of vapor diffusion between the crystal growth solution and the reservoir. The devices can comprise a channel which can be of varying lengths or geometries. The channel can either be static or controlled actively or dynamically. Alternatively, the diffusion pathways are provided by the material of the device itself. The device comprises porous and/or water absorbing materials through which the vapor can diffuse. The vapor diffusion rate can be controlled by the thickness or material of the device, or a combination of both.
Inventors:
BRAY TERRY LEE (US)
Application Number:
PCT/US2001/015308
Publication Date:
April 04, 2002
Filing Date:
May 11, 2001
Export Citation:
Assignee:
UAB RESEARCH FOUNDATION (US)
BRAY TERRY LEE (US)
BRAY TERRY LEE (US)
International Classes:
C30B7/00; (IPC1-7): C30B29/58; C30B7/00
Foreign References:
| US4919899A | 1990-04-24 | |||
| US5256241A | 1993-10-26 | |||
| US5096676A | 1992-03-17 | |||
| US4917707A | 1990-04-17 | |||
| US5641681A | 1997-06-24 | |||
| US5961934A | 1999-10-05 | |||
| US4886646A | 1989-12-12 | |||
| US5552127A | 1996-09-03 |
Other References:
SHU Z-Y ET AL: "In situ measurement and dynamic control of the evaporation rate in vapor diffusion crystallization of proteins", JOURNAL OF CRYSTAL GROWTH, NORTH-HOLLAND PUBLISHING CO. AMSTERDAM, NL, vol. 192, no. 1-2, 15 August 1998 (1998-08-15), pages 282 - 289, XP004141561, ISSN: 0022-0248
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