Title:
METHOD AND DEVICE FOR MARKING BIOMOLECULES
Document Type and Number:
WIPO Patent Application WO2005064335
Kind Code:
A3
Abstract:
The invention relates to a method which is used to efficiently mark proteins with the help of a micromixer, in addition to a device which enables said inventive method to be carried out in an economical manner and with additional auxiliary agents.
Inventors:
AZZAWI ALEXANDER (DE)
DERSCHUM STEFAN (DE)
DERSCHUM STEFAN (DE)
Application Number:
PCT/EP2004/012172
Publication Date:
September 22, 2005
Filing Date:
October 28, 2004
Export Citation:
Assignee:
EHRFELD MIKROTECHNIK BTS GMBH (DE)
AZZAWI ALEXANDER (DE)
DERSCHUM STEFAN (DE)
AZZAWI ALEXANDER (DE)
DERSCHUM STEFAN (DE)
International Classes:
B01F13/00; B01J19/00; B01L99/00; G01N33/533; (IPC1-7): G01N33/533; B01J19/00; B01F13/00
Domestic Patent References:
| WO1996040398A1 | 1996-12-19 |
Other References:
SPIKMANS VALERIE ET AL: "On-line on-chip post-column derivatisation reactions for pre-ionisation of analytes and cluster analysis in gradient micro-liquid chromatography/electrospray mass spectrometry.", RAPID COMMUNICATIONS IN MASS SPECTROMETRY : RCM. 2002, vol. 16, no. 14, 2002, pages 1377 - 1388, XP009049801, ISSN: 0951-4198
KLING KERSTIN ET AL: "Visualization of micro-and macromixing in liquid mixtures of reacting components", PROC. ASME/JSME JOINT FLUIDS ENG. CONF.; PROCEEDINGS OF THE ASME/JSME JOINT FLUIDS ENGINEERING CONFERENCE 2003, vol. 2 C, 2003, pages 2329 - 2335, XP009049802
BRINKLEY M: "A BRIEF SURVEY OF METHODS FOR PREPARING PROTEIN CONJUGATES WITH DYES, HAPTENS, AND CROSS-LINKING REAGENTS", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 3, no. 1, January 1992 (1992-01-01), pages 2 - 13, XP000261480, ISSN: 1043-1802
HAUGLAND R P: "COUPLING OF MONOCLONAL ANTIBODIES WITH FLUOROPHORES", METHODS IN MOLECULAR BIOLOGY, HUMANA PRESS INC., CLIFTON, NJ, US, vol. 45, 1995, pages 205 - 221, XP009020645
KLING KERSTIN ET AL: "Visualization of micro-and macromixing in liquid mixtures of reacting components", PROC. ASME/JSME JOINT FLUIDS ENG. CONF.; PROCEEDINGS OF THE ASME/JSME JOINT FLUIDS ENGINEERING CONFERENCE 2003, vol. 2 C, 2003, pages 2329 - 2335, XP009049802
BRINKLEY M: "A BRIEF SURVEY OF METHODS FOR PREPARING PROTEIN CONJUGATES WITH DYES, HAPTENS, AND CROSS-LINKING REAGENTS", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 3, no. 1, January 1992 (1992-01-01), pages 2 - 13, XP000261480, ISSN: 1043-1802
HAUGLAND R P: "COUPLING OF MONOCLONAL ANTIBODIES WITH FLUOROPHORES", METHODS IN MOLECULAR BIOLOGY, HUMANA PRESS INC., CLIFTON, NJ, US, vol. 45, 1995, pages 205 - 221, XP009020645
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