Title:
METHOD FOR EVALUATING OF METASTASIS OR RISK OF RECURRENCE OF BREAST CANCER
Document Type and Number:
WIPO Patent Application WO/2015/115545
Kind Code:
A1
Abstract:
Provided is a technique for objectively, rapidly and highly accurately evaluating the presence or absence of the effect of a medicine, the risk of recurrence or the possibility of metastasis in a chemical therapy for breast cancer. A method for evaluating the metastasis of breast cancer or the risk of recurrence of breast cancer in a breast cancer patient, said method comprising a step of measuring the level of expression of at least one expression product of DNA containing a transcription initiation domain in a biological sample derived from a cancer tissue separated from the patient.
Inventors:
SHIMIZU SATORU (JP)
MIYAGI YOHEI (JP)
OHTSU TAKASHI (JP)
SAITO MITSUE (JP)
HAYASHIZAKI YOSHIHIDE (JP)
ITO MASAYOSHI (JP)
KAWAJI HIDEYA (JP)
OOMIYA HIROKO (JP)
MIYAGI YOHEI (JP)
OHTSU TAKASHI (JP)
SAITO MITSUE (JP)
HAYASHIZAKI YOSHIHIDE (JP)
ITO MASAYOSHI (JP)
KAWAJI HIDEYA (JP)
OOMIYA HIROKO (JP)
Application Number:
PCT/JP2015/052522
Publication Date:
August 06, 2015
Filing Date:
January 29, 2015
Export Citation:
Assignee:
KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP)
JUNTENDO EDUCATIONAL FOUNDATION (JP)
RIKEN (JP)
JUNTENDO EDUCATIONAL FOUNDATION (JP)
RIKEN (JP)
International Classes:
C12N15/09; C12Q1/68; G01N33/574
Foreign References:
| JP2007530075A | 2007-11-01 | |||
| JP2007267692A | 2007-10-18 | |||
| JP2013099253A | 2013-05-23 |
Other References:
CHEN L.H. ET AL.: "Identification of prognostic genes for recurrent risk prediction in triple negative breast cancer patients in Taiwan .", PLOS ONE, vol. 6, no. 11, 2011, pages E28222, XP055065593
KOJI SENUMA ET AL.: "PATHOLOGICAL THERAPEUTIC EFFECTS OF PREOPERATIVE SYSTEMIC CHEMOTHERAPY ASSOCIATED WITH BIOMARKERS FOR PRIMARY BREAST CANCER", JUNTENDO MEDICAL JOURNAL, vol. 59, no. 3, 2013, pages 251 - 259
MUSTACCHI G. ET AL.: "Identification and validation of a new set of five genes for prediction of risk in early breast cancer.", INT.J.MOL.SCI., vol. 14, no. 5, 2013, pages 9686 - 9702, XP055090028
KOJI SENUMA ET AL.: "PATHOLOGICAL THERAPEUTIC EFFECTS OF PREOPERATIVE SYSTEMIC CHEMOTHERAPY ASSOCIATED WITH BIOMARKERS FOR PRIMARY BREAST CANCER", JUNTENDO MEDICAL JOURNAL, vol. 59, no. 3, 2013, pages 251 - 259
MUSTACCHI G. ET AL.: "Identification and validation of a new set of five genes for prediction of risk in early breast cancer.", INT.J.MOL.SCI., vol. 14, no. 5, 2013, pages 9686 - 9702, XP055090028
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
Patent business corporation Alga patent firm (JP)
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