Title:
METHOD FOR EVALUATING RISK OF STOMACH CANCER ONSET
Document Type and Number:
WIPO Patent Application WO/2023/074869
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a method for evaluating the risk of stomach cancer onset. Specifically, the present invention is a method for evaluating the risk of stomach cancer onset, wherein the risk of stomach cancer onset for a test subject is determined to be high when bacteria belonging to the Fusobacterium genus or bacteria belonging to the Neisseria genus are detected in a specimen derived from said test subject. Furthermore, the present invention provides a kit for evaluating the risk of stomach cancer onset, said kit including a means for detecting bacteria belonging to the Fusobacterium genus or bacteria belonging to the Neisseria genus.
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Inventors:
HAYAKAWA YOKU (JP)
NIIKURA RYOTA (JP)
NIIKURA RYOTA (JP)
Application Number:
PCT/JP2022/040474
Publication Date:
May 04, 2023
Filing Date:
October 28, 2022
Export Citation:
Assignee:
UNIV TOKYO (JP)
International Classes:
C12Q1/04; A61K45/00; A61P31/04; A61P35/00; C12Q1/12; G01N33/50
Foreign References:
| CN110777213A | 2020-02-11 |
Other References:
NIIKURA, RYOTA ET AL.: "WS1-7 Association between gastric cancer after eradication of Helicobacter pylori and Fusobacterium Neisseria genus", THE 27TH ANNUAL MEETING OF THE JAPANESE HELICOBACTER SOCIETY PROGRAM AND ABSTRACTS; 2021.09.24-26, JAPANESE HELICOBACTER SOCIETY, JP, 31 August 2021 (2021-08-31) - 26 September 2021 (2021-09-26), JP, pages 185, XP009546671
ZIEBARTH D, SPIEGELHALDER, BARTSCH: "N-nitrosation of medicinal drugs catalysed by bacteria from human saliva and gastro-intestinal tract, including Helicobacter pylori", CARCINOGENESIS, OXFORD UNIVERSITY PRESS, GB, vol. 18, no. 2, 1 February 1997 (1997-02-01), GB , pages 383 - 389, XP093061734, ISSN: 0143-3334, DOI: 10.1093/carcin/18.2.383
LI YONGHONG, WANG JIA, WANG MENGGE, GAO YONGSHUN, JIN CHENG-YUN, SHI XIAOJING, JI BOYANG, WEI YONGJUN, LIU HONGMIN: "Microbial profiling identifies potential key drivers in gastric cancer patients", BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, DIAGNOSIS PRESS, SOFIA, BG, vol. 35, no. 1, 1 January 2021 (2021-01-01), BG , pages 496 - 503, XP093061735, ISSN: 1310-2818, DOI: 10.1080/13102818.2021.1896384
ZIEBARTH D, SPIEGELHALDER, BARTSCH: "N-nitrosation of medicinal drugs catalysed by bacteria from human saliva and gastro-intestinal tract, including Helicobacter pylori", CARCINOGENESIS, OXFORD UNIVERSITY PRESS, GB, vol. 18, no. 2, 1 February 1997 (1997-02-01), GB , pages 383 - 389, XP093061734, ISSN: 0143-3334, DOI: 10.1093/carcin/18.2.383
LI YONGHONG, WANG JIA, WANG MENGGE, GAO YONGSHUN, JIN CHENG-YUN, SHI XIAOJING, JI BOYANG, WEI YONGJUN, LIU HONGMIN: "Microbial profiling identifies potential key drivers in gastric cancer patients", BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, DIAGNOSIS PRESS, SOFIA, BG, vol. 35, no. 1, 1 January 2021 (2021-01-01), BG , pages 496 - 503, XP093061735, ISSN: 1310-2818, DOI: 10.1080/13102818.2021.1896384
Attorney, Agent or Firm:
OKUHARA Koji (JP)
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