Title:
METHOD OF EXAMINING PERIODONTAL DISEASE
Document Type and Number:
WIPO Patent Application WO/2002/079780
Kind Code:
A1
Abstract:
A method of examining periodontal disease which involves the step of subjecting a sample collected from the oral cavity of a subject to an immunoassay with the use of an anti-8-hydroxydeoxyguanosine antibody and thus quantifying 8-hydroxydeoxyguanosine. Thus, periodontal disease can be conveniently examined.
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Inventors:
SUGANO NAOYUKI (JP)
Application Number:
PCT/JP2002/003077
Publication Date:
October 10, 2002
Filing Date:
March 28, 2002
Export Citation:
Assignee:
UNIV NIHON (JP)
SUGANO NAOYUKI (JP)
SUGANO NAOYUKI (JP)
International Classes:
G01N33/569; (IPC1-7): G01N33/53
Other References:
SCHMIDT ET AL.: "AGEs induce oxidant stress in the gingiva", JOURNAL OF PERIODONTAL RESEARCH, vol. 31, no. 7, 1996, pages 508 - 515, XP002951563
TOYOKUNI ET AL.: "Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody", LABORATORY INVESTIGATION, vol. 76, no. 3, 1997, pages 365 - 374, XP002951569
YIN ET AL.: "Determination of 8-hydroxydeoxyguanosine by an immunoaffinity chromatography-monoclonal antibody-based ELISA", FREE RADICAL BIOLOGY & MEDICINE, vol. 18, no. 6, 1995, pages 1023 - 1032, XP002951570
TOYOKUNI ET AL.: "Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody", LABORATORY INVESTIGATION, vol. 76, no. 3, 1997, pages 365 - 374, XP002951569
YIN ET AL.: "Determination of 8-hydroxydeoxyguanosine by an immunoaffinity chromatography-monoclonal antibody-based ELISA", FREE RADICAL BIOLOGY & MEDICINE, vol. 18, no. 6, 1995, pages 1023 - 1032, XP002951570
Attorney, Agent or Firm:
Kawamata, Shizuko (2156 Matsudo Matsudo-shi, Chiba, JP)
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