Title:
METHOD FOR EXTRACTING AND PURIFYING COENZYME Q10 AND COENZYME Q10 PREPARED THEREBY
Document Type and Number:
WIPO Patent Application WO/2020/015316
Kind Code:
A1
Abstract:
Disclosed are a method for extracting and purifying coenzyme Q10 and coenzyme Q10 prepared thereby. The method extracts and purifies coenzyme Q10 from coenzyme Q10 bacteria and comprises the steps of extracting, precipitating, decoloring, and chromatographic refining, thereby targetedly removing impurities, such as bacterial pigments, nonpolar lipids, neutral lipids, polar lipids, and quinone homologs. The method has simple operation steps and less product loss. The purity of the product coenzyme Q10 thereof can be more than 99.8%, and the total yield can be more than 98.5%.
Inventors:
MIN YI (CN)
CHEN ZHAOFENG (CN)
ZHANG JINYANG (CN)
TU SHICHUN (CN)
HU WEIJIANG (CN)
CHEN ZHAOFENG (CN)
ZHANG JINYANG (CN)
TU SHICHUN (CN)
HU WEIJIANG (CN)
Application Number:
PCT/CN2018/123214
Publication Date:
January 23, 2020
Filing Date:
December 24, 2018
Export Citation:
Assignee:
ZHEJIANG NHU CO LTD (CN)
HEILONGJIANG NHU BIOTECHNOLOGY COMPANY LTD (CN)
SHANGYU NHU BIO CHEM CO LTD (CN)
HEILONGJIANG NHU BIOTECHNOLOGY COMPANY LTD (CN)
SHANGYU NHU BIO CHEM CO LTD (CN)
International Classes:
C07C46/10; C07C50/28
Foreign References:
| CN104694613A | 2015-06-10 |
Other References:
CAO, XUELI ET AL.: "Purification of coenzyme Q10 from fermentation extract: High-speed counter-current chromatography versus silica gel column chromatography", J. CHROMATOGR. A, vol. 1127, 22 June 2006 (2006-06-22), pages 92 - 96, XP024967634
YANG, . ZHEN'NI ET AL.: "An Efficient Purification Process of Coenzyme Q10", INFORMATION RECORDING MATERIALS, vol. 17, no. 1, 29 February 2016 (2016-02-29), pages 28
YANG, . ZHEN'NI ET AL.: "An Efficient Purification Process of Coenzyme Q10", INFORMATION RECORDING MATERIALS, vol. 17, no. 1, 29 February 2016 (2016-02-29), pages 28
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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