Title:
METHOD FOR EXTRACTION OF COMPOUND CONTAINING SIALIC ACID FROM PLANT
Document Type and Number:
WIPO Patent Application WO/2011/043107
Kind Code:
A1
Abstract:
Disclosed is a method for extracting a compound containing sialic acid from a raw material that is readily available and does not has undergo the contamination by any animal-affecting pathogen (i.e., has high safety), wherein the method enables the extraction of the compound at low cost and in a simple manner without requiring any reagent that is toxic to human bodies and environments.
Specifically disclosed is a method for extracting a compound containing sialic acid, which is characterized by comprising crudely extracting a soluble component from a plant (particularly a seed of a crop or bean) or a processed product thereof with water, an alcohol or a hydrous alcohol and separating and collecting the compound from the crude extract by means of dialysis, salting out or a chromatography column.
Inventors:
KAWASE SHIN-ICHIRO (JP)
Application Number:
PCT/JP2010/060010
Publication Date:
April 14, 2011
Filing Date:
June 14, 2010
Export Citation:
Assignee:
INC ADMIN AGENCY NARO (JP)
KAWASE SHIN-ICHIRO (JP)
KAWASE SHIN-ICHIRO (JP)
International Classes:
C07H7/027; C07H1/08
Domestic Patent References:
| WO2009130923A1 | 2009-10-29 |
Foreign References:
| JPH0899988A | 1996-04-16 | |||
| JPH06293788A | 1994-10-21 | |||
| JP2001514865A | 2001-09-18 | |||
| JP2008005778A | 2008-01-17 | |||
| JP2003129083A | 2003-05-08 |
Other References:
MAYER F.C. ET AL.: "Occurrence of Sialic Acids in Plant Seeds", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 108, 1964, pages 356 - 365, XP024805565
ONODERA KONOSHIN ET AL.: "Sialic Acid and Related Substances Part IV Sialic Acid", CONTENT OF SOME BIOLOGICAL MATERIALS AGR. BIOL. CHEM., vol. 30, no. 11, 1966, pages 1170 - 1172, XP008137187
SUNADA SABURO ET AL.: "Studies on the sugarchain of glycol-conjugates.", SUGIYAMA CHEMICAL & INDUSTRIAL LABORATORY ANNUAL REPORT, vol. 1989, 1989, pages 1 - 20, XP008153425
STURGEON ROBERT J.: "Affinity Chromatography of Sialoglyco-proteins, utilising the interraction of Serotonin with N-acetyl", CARBOHYDTRATE RESEARCH, vol. 103, 1982, pages 213 - 219, XP008137040
SHIN SEIKAGAKU JIKKEN: "Koza 4 Lipid", GLYCOLIPID, vol. III, 1990, pages L49
CARBOHYDRATE RESEARCH, vol. 103, 1982, pages 213 - 219
GANGLIOSIDE KENKYUHOU, vol. I, 1995, pages 7 - 25
NATURE BIOTECHNOLOGY, vol. 21, 2003, pages 1470 - 1471
NATURE BIOTECHNOLOGY, vol. 22, 2004, pages 1351 - 1352
ONODERA KONOSHIN ET AL.: "Sialic Acid and Related Substances Part IV Sialic Acid", CONTENT OF SOME BIOLOGICAL MATERIALS AGR. BIOL. CHEM., vol. 30, no. 11, 1966, pages 1170 - 1172, XP008137187
SUNADA SABURO ET AL.: "Studies on the sugarchain of glycol-conjugates.", SUGIYAMA CHEMICAL & INDUSTRIAL LABORATORY ANNUAL REPORT, vol. 1989, 1989, pages 1 - 20, XP008153425
STURGEON ROBERT J.: "Affinity Chromatography of Sialoglyco-proteins, utilising the interraction of Serotonin with N-acetyl", CARBOHYDTRATE RESEARCH, vol. 103, 1982, pages 213 - 219, XP008137040
SHIN SEIKAGAKU JIKKEN: "Koza 4 Lipid", GLYCOLIPID, vol. III, 1990, pages L49
CARBOHYDRATE RESEARCH, vol. 103, 1982, pages 213 - 219
GANGLIOSIDE KENKYUHOU, vol. I, 1995, pages 7 - 25
NATURE BIOTECHNOLOGY, vol. 21, 2003, pages 1470 - 1471
NATURE BIOTECHNOLOGY, vol. 22, 2004, pages 1351 - 1352
Attorney, Agent or Firm:
YANO HIROYA (JP)
Hironari Yano (JP)
Hironari Yano (JP)
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