Title:
METHOD FOR FORMING EMBRYOID BODY OF PLURIPOTENT STEM CELLS AND COMPOSITION FOR FORMING EMBRYOID BODY OF PLURIPOTENT STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2017/073761
Kind Code:
A1
Abstract:
Provided are uses for collagen decomposition products or atelocollagen decomposition products having novel physiological functions. A method for forming an embryoid body of pluripotent stem cells according to an embodiment of the present invention comprises a step for culturing pluripotent stem cells together with collagen decomposition products or atelocollagen decomposition products, wherein the decomposition products include at least a portion of the triple-helical domain of the collagen or atelocollagen.
Inventors:
MORIMOTO KOICHI (JP)
KUNII SAORI (JP)
KUNII SAORI (JP)
Application Number:
PCT/JP2016/082150
Publication Date:
May 04, 2017
Filing Date:
October 28, 2016
Export Citation:
Assignee:
UNIV KINKI (JP)
International Classes:
C12N5/073; C07K4/12; C07K14/78
Domestic Patent References:
| WO2004020470A1 | 2004-03-11 | |||
| WO2008026548A1 | 2008-03-06 | |||
| WO2007075807A2 | 2007-07-05 |
Foreign References:
| US20050054100A1 | 2005-03-10 | |||
| JP2005514944A | 2005-05-26 | |||
| US20080044848A1 | 2008-02-21 |
Other References:
DATE YASUSHI ET AL.: "Major amino acids in collagen hydrolysate regulate the differentiation of mouse embryoid bodies", J. BIOSCI. BIOENG., vol. 116, no. 3, 2013, pages 386 - 390, XP055382235
MATSUOKA YASUHIRO ET AL.: "Insufficient Folding of Type IV Collagen and Formation of Abnormal Basement Membrane-like Structure in Embryoid Bodies Derived from Hsp47-Null Embryonic Stem Cells", MOLECULAR BIOLOGY OF THE CELL, vol. 15, 2004, pages 4467 - 4475, XP055382237
SAORI KUNII ET AL.: "Comparison of Biochemical Properties of Novel Actinidain-hydrolyzed Collagen and Pepsin-hydrolzyed Collagen", MEM. INSTITUTE OF ADVANCED TECHNOLOGY, 2005, pages 19 - 28
MATSUOKA YASUHIRO ET AL.: "Insufficient Folding of Type IV Collagen and Formation of Abnormal Basement Membrane-like Structure in Embryoid Bodies Derived from Hsp47-Null Embryonic Stem Cells", MOLECULAR BIOLOGY OF THE CELL, vol. 15, 2004, pages 4467 - 4475, XP055382237
SAORI KUNII ET AL.: "Comparison of Biochemical Properties of Novel Actinidain-hydrolyzed Collagen and Pepsin-hydrolzyed Collagen", MEM. INSTITUTE OF ADVANCED TECHNOLOGY, 2005, pages 19 - 28
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
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