Title:
METHOD OF INDUCING A CTL RESPONSE
Document Type and Number:
WIPO Patent Application WO2002062368
Kind Code:
A8
Abstract:
Disclosed herein are methods for inducing an immunological CTL response to an antigen by sustained, regular delivery of the antigen to a mammal so that the antigen reaches the lymphatic system. Antigen is delivered at a level sufficient to induce an immunologic CTL response in a mammal and the level of the antigen in the mammal's lymphatic system is maintained over time sufficient to maintain the immunologic CTL response. Also disclosed is an article of manufacture for delivering an antigen that induces a CTL response in an animal.
Inventors:
KUNDIG THOMAS M (CH)
SIMARD JOHN J L (US)
SIMARD JOHN J L (US)
Application Number:
PCT/US2002/002033
Publication Date:
November 20, 2003
Filing Date:
January 22, 2002
Export Citation:
Assignee:
MANNKIND CORP (US)
International Classes:
A61K39/00; A61K39/12; A61P31/00; A61P35/00; C07K14/08; A61K9/00; A61K38/00; (IPC1-7): A61K39/00; A61P35/00; A61P31/00
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