Title:
METHOD OF INHIBITING SURGICAL SITE INFECTION AND COLUMN TO BE USED THEREFOR
Document Type and Number:
WIPO Patent Application WO/2006/008906
Kind Code:
A1
Abstract:
It is intended to provide a method of inhibiting surgical site infection (SSI) which occurs at an extremely high ratio in surgical operations, in particular, operations on the digestive system and a column therefor. Namely, a method of inhibiting surgical site infection which comprises (a) the step of administering a chemotherapeutic for treating and/or preventing surgical site infection, and (b) the step of collecting the blood from the patient having the surgical operation within 24 hours after the completion of the operation, removing leucocytes including neutrophils from the blood and then returning the leucocyte-free blood into the patient; and a column for blood circulation to be used for inhibiting surgical site infection within 24 hours after the completion of a surgical operation on a digestive organ which is packed with a carrier having an affinity for leucocytes including neutrophils.
Inventors:
KUSUNOKI MASATO (JP)
MIKI CHIKAO (JP)
YOSHIYAMA SHIGEYUKI (JP)
MIKI CHIKAO (JP)
YOSHIYAMA SHIGEYUKI (JP)
Application Number:
PCT/JP2005/011501
Publication Date:
January 26, 2006
Filing Date:
June 23, 2005
Export Citation:
Assignee:
ASAHI KASEI MEDICAL CO LTD (JP)
KUSUNOKI MASATO (JP)
MIKI CHIKAO (JP)
YOSHIYAMA SHIGEYUKI (JP)
KUSUNOKI MASATO (JP)
MIKI CHIKAO (JP)
YOSHIYAMA SHIGEYUKI (JP)
International Classes:
A61K35/14; (IPC1-7): A61M1/36; A61K31/43; A61K31/546; A61K35/14; A61K45/00; A61M1/02
Foreign References:
| JPH01129855A | 1989-05-23 | |||
| JP2000217908A | 2000-08-08 | |||
| JPH04240456A | 1992-08-27 | |||
| JPH08103493A | 1996-04-23 |
Other References:
YOSHIYAMA S. ET AL: "Kaiyosei Daichoen Jutsugo mobidity Kaizen no Tameno Shujutsuki Hakkekkyu Jokyo Ryoho ni Kansuru prospective trial", THE JAPANESE JOURNAL OF GASTROENTEROLOGICAL SURGERY, vol. 37, no. 7, 1 July 2004 (2004-07-01), pages 240, XP002998937
MANGRAM A.J. ET AL: "Guideline for prevention of surgical site infection, 1999", INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, vol. 20, no. 4, 1999, pages 247 - 278, XP002998938
MANGRAM A.J. ET AL: "Guideline for prevention of surgical site infection, 1999", INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, vol. 20, no. 4, 1999, pages 247 - 278, XP002998938
Attorney, Agent or Firm:
SIKs & Co. (Kyobashi-Nisshoku Bldg., 8-7, Kyobashi
1-chome,, Chuo-k, Tokyo 31, JP)
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