Title:
METHOD FOR MEASURING GLYCATED HEMOGLOBIN
Document Type and Number:
WIPO Patent Application WO/2018/221446
Kind Code:
A1
Abstract:
A method for measuring glycated hemoglobin in a hemoglobin-containing sample characterized in that an enzyme that catalyzes a reaction that oxidizes glycated amino acids or glycated peptides without oxidizing glycated hemoglobin to generate hydrogen peroxide is added to a hemoglobin-containing sample to generate hydrogen peroxide; after eliminating the generated hydrogen peroxide, an enzyme that catalyzes a reaction that oxidizes glycated hemoglobin to generate hydrogen peroxide is added to generate hydrogen peroxide; and the generated hydrogen peroxide is measured.
Inventors:
SOYA HARUYO (JP)
HAYASHI TATSUYA (JP)
OGAWA TOMOMI (JP)
KATAYAMA YUKI (JP)
HAYASHI TATSUYA (JP)
OGAWA TOMOMI (JP)
KATAYAMA YUKI (JP)
Application Number:
PCT/JP2018/020319
Publication Date:
December 06, 2018
Filing Date:
May 28, 2018
Export Citation:
Assignee:
KYOWA MEDEX CO LTD (JP)
International Classes:
C12M1/34; C12Q1/26; C12Q1/28; C12Q1/30; G01N33/72
Domestic Patent References:
| WO2015005258A1 | 2015-01-15 | |||
| WO2015060429A1 | 2015-04-30 | |||
| WO2007072941A1 | 2007-06-28 | |||
| WO2015005258A1 | 2015-01-15 | |||
| WO2015005257A1 | 2015-01-15 | |||
| WO2015060429A1 | 2015-04-30 | |||
| WO2003033729A1 | 2003-04-24 | |||
| WO2010041715A1 | 2010-04-15 |
Foreign References:
| JP2010011876A | 2010-01-21 | |||
| JP2007289202A | 2007-11-08 | |||
| JP2017107002A | 2017-06-15 | |||
| JP2011045389A | 2011-03-10 |
Other References:
OGAWA, NORIYUKI ET AL.: "3J002 Creation of hemoglobin A1c direct oxidase by structure-based site specific and random mutagenesis", ANNUAL MEETING OF THE JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, 2016, no. 3J002, 5 March 2016 (2016-03-05), Japan, pages 3J002, XP009517798, ISSN: 2186-7976
CLIN CHEM LAB MED, vol. 36, 1998, pages 299 - 308
DIABETES, vol. 27, no. 2, 1978, pages 102 - 107
JAPANESE JOURNAL OF CLINICAL LABORATORY AUTOMATION, vol. 18, no. 4, 1993, pages 620
J. AGRIC. FOOD CHEM., vol. 24, no. 1, 1976, pages 70 - 73
See also references of EP 3636767A4
CLIN CHEM LAB MED, vol. 36, 1998, pages 299 - 308
DIABETES, vol. 27, no. 2, 1978, pages 102 - 107
JAPANESE JOURNAL OF CLINICAL LABORATORY AUTOMATION, vol. 18, no. 4, 1993, pages 620
J. AGRIC. FOOD CHEM., vol. 24, no. 1, 1976, pages 70 - 73
See also references of EP 3636767A4
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
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