Title:
METHOD FOR MEDIATING MIRNA OVEREXPRESSION BASED ON MAMMALIAN VIRUS
Document Type and Number:
WIPO Patent Application WO/2019/227262
Kind Code:
A1
Abstract:
Provided is a method for mediating miRNA overexpression based on a mammalian virus. The method achieves the overexpression of an endogenous target miRNA in tumor cells mainly by infecting the tumor cells with the mammalian virus carrying a target miRNA precursor fragment.
Inventors:
MAO JIYAN (CN)
Application Number:
PCT/CN2018/088537
Publication Date:
December 05, 2019
Filing Date:
May 26, 2018
Export Citation:
Assignee:
SHENZHEN BIOCAN TECH CO LTD (CN)
International Classes:
C12N15/63; C12N15/67; C12N15/85; C12N15/86
Foreign References:
| CN104306992A | 2015-01-28 | |||
| US20140303025A1 | 2014-10-09 |
Other References:
BAO, YONGZHENG, 02, 15 February 2017 (2017-02-15)
YONGZHENG: "Overexpression of miR-664 is associated with enhanced osteosarcoma cell migration and invasion ability via targeting SOX7", CLIN EXP MED, vol. 17, no. 1, 29 October 2015 (2015-10-29), pages 51 - 58, XP036147300, ISSN: 1940-5901
YONGZHENG: "Overexpression of miR-664 is associated with enhanced osteosarcoma cell migration and invasion ability via targeting SOX7", CLIN EXP MED, vol. 17, no. 1, 29 October 2015 (2015-10-29), pages 51 - 58, XP036147300, ISSN: 1940-5901
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