Title:
METHOD FOR MONITORING DONAR DNA FRACTION
Document Type and Number:
WIPO Patent Application WO/2023/116717
Kind Code:
A1
Abstract:
Provided is a method for detecting donor cfDNA fraction in a sample of a recipient. Also provided is a method for detecting over-represented SNP(s)of donor cfDNA in an identified region.
Inventors:
HE JIANXING (CN)
LIU LIPING (CN)
HUANG LIYAN (CN)
LIU LIPING (CN)
HUANG LIYAN (CN)
Application Number:
PCT/CN2022/140435
Publication Date:
June 29, 2023
Filing Date:
December 20, 2022
Export Citation:
Assignee:
FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (CN)
International Classes:
C12N5/00; C12M1/34; C12N15/11; C12Q1/68
Domestic Patent References:
| WO2014194113A2 | 2014-12-04 | |||
| WO2017045654A1 | 2017-03-23 | |||
| WO2020118046A1 | 2020-06-11 |
Foreign References:
| CN107254514A | 2017-10-17 | |||
| CN106480170A | 2017-03-08 | |||
| CN110396560A | 2019-11-01 | |||
| CN110452975A | 2019-11-15 | |||
| CN112458162A | 2021-03-09 | |||
| US20190203285A1 | 2019-07-04 |
Other References:
LUO JIAQI, LIU LIPING, CHEN LINGXI, XU XIN, WANG YANFEI, WEI BING, JU CHUNRONG, WANG XUEDONG, HUANG LIYAN, ZENG WENCHUANG, MIAO XI: "Over‐shedding of donor‐derived cell‐free DNA at immune‐related regions into plasma of lung transplant recipient", CLINICAL AND TRANSLATIONAL MEDICINE, INTERNATIONAL SOCIETY FOR TRANSLATIONAL MEDICINE, SE, vol. 12, no. 1, 1 January 2022 (2022-01-01), SE , XP093073745, ISSN: 2001-1326, DOI: 10.1002/ctm2.622
Attorney, Agent or Firm:
IPSUNNY (CN)
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