Title:
METHOD FOR PERFORMING ADDITION REACTION BETWEEN ACETYLENE AND KETONE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2021/051275
Kind Code:
A1
Abstract:
Disclosed in the present invention is a method for performing an addition reaction between acetylene and a ketone compound. The method comprises the following steps: S1, providing a continuous reaction device, the continuous reaction device comprising a plurality of bubble tubular reactors arranged in series; the plurality of bubble tubular reactors being connected to each other by means of a connecting tube; S2, introducing a raw material solution containing the ketone compound and alkaline into the plurality of bubble tubular reactors; and S3, under the normal pressure, bubbling acetylene from the bottom of the first bubble tubular reactor to perform the addition reaction. By applying the technical solution of the present invention, acetylene reacts with the ketone compound in the plurality of bubble tubular reactors arranged in series, which can ensure the sufficient gas-liquid contact time, and thus making full use of the acetylene gas, improving the utilization rate thereof, effectively reducing the amount of acetylene, reducing costs, and further improving the security.
Inventors:
HONG HAO (US)
LU JIANGPING (CN)
FENG XICHUN (CN)
ZHANG XIN (CN)
YAN BO (CN)
LU JIANGPING (CN)
FENG XICHUN (CN)
ZHANG XIN (CN)
YAN BO (CN)
Application Number:
PCT/CN2019/106220
Publication Date:
March 25, 2021
Filing Date:
September 17, 2019
Export Citation:
Assignee:
ASYMCHEM LIFE SCIENCE TIANJIN CO LTD (CN)
International Classes:
C07C29/42
Domestic Patent References:
| WO2010119448A1 | 2010-10-21 |
Foreign References:
| CN110540489A | 2019-12-06 | |||
| CN1312784A | 2001-09-12 | |||
| CN109796304A | 2019-05-24 | |||
| CN102076701A | 2011-05-25 | |||
| CN109897010A | 2019-06-18 |
Other References:
BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 14, no. 23, 2004, pages 5855 - 5857
ORGANIC LETTERS, vol. 15, no. 2, 2013, pages 238 - 241
See also references of EP 4032873A4
ORGANIC LETTERS, vol. 15, no. 2, 2013, pages 238 - 241
See also references of EP 4032873A4
Attorney, Agent or Firm:
KANGXIN PARTNERS, P.C. (CN)
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