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Title:
METHOD FOR PREDICTING THE RESPONSE OF NON-SMALL CELL LUNG CANCER PATIENTS TO TARGETED PHARMACOTHERAPY
Document Type and Number:
WIPO Patent Application WO/2010/116003
Kind Code:
A3
Abstract:
The present invention relates to a method for determining or predicting the response of a patient diagnosed with non small cell lung cancer to targeted pharmacotherapy. The present invention also aims to provide methods and devices for predicting the response of patients diagnosed with non small cell lung cancer to specific medicaments. More specifically, the present invention provides methods which measure kinase activity by studying phosphorylation levels and profiles and inhibitions thereof by drugs in samples of said patients.

Inventors:
DE WIJN RICHARD (NL)
RUIJTENBEEK ROBBY (NL)
HILHORST MARIA HELENA (NL)
VAN DEN HEUVEL MICHAEL MARIA (NL)
KLOMP HOUKE MARIAN (NL)
Application Number:
PCT/EP2010/054772
Publication Date:
February 03, 2011
Filing Date:
April 12, 2010
Export Citation:
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Assignee:
PAMGENE BV (NL)
STICHTING NL KANKER INST (NL)
DE WIJN RICHARD (NL)
RUIJTENBEEK ROBBY (NL)
HILHORST MARIA HELENA (NL)
VAN DEN HEUVEL MICHAEL MARIA (NL)
KLOMP HOUKE MARIAN (NL)
International Classes:
G01N33/574; C12Q1/48; G01N33/50; G01N33/52
Domestic Patent References:
WO2009012140A22009-01-22
WO2008049930A22008-05-02
WO2005035003A22005-04-21
WO2003107003A12003-12-24
Foreign References:
US20070254295A12007-11-01
US20060019284A12006-01-26
Attorney, Agent or Firm:
DE CLERCQ, Ann et al. (E. Gevaertdreef 10a, Sint-Martens-Latem, BE)
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