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Title:
METHOD FOR PREPARATION OF (2R, 3S)-2-(BENZO[D]IMIDAZOLYLPROPYL)PIPERIDIN-3-OL DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2023/113534
Kind Code:
A1
Abstract:
The present invention relates to a method for preparation of (2R, 3S)-2-(benzo[d]imidazolylpropyl)piperidin-3-ol derivatives. The preparation method according to the present invention has the advantage of preparing the compound in a high yield even by simplified processes.

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Inventors:
LEE JOON-HWAN (KR)
CHO MIN JAE (KR)
PARK JOON SEOK (KR)
Application Number:
PCT/KR2022/020582
Publication Date:
June 22, 2023
Filing Date:
December 16, 2022
Export Citation:
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Assignee:
DAEWOONG PHARMACEUTICAL CO LTD (KR)
International Classes:
C07D401/06; C07D211/42
Domestic Patent References:
WO2010018134A12010-02-18
Foreign References:
KR102084772B12020-03-04
Other References:
SHUAI QI, LI JUN, ZHAO FENG, SU WEIKE, DENG GUOJUN: "Metal-free chemoselective reduction of nitroaromatics to anilines via hydrogen transfer strategy", CHEMICAL PAPERS, SPRINGER INTERNATIONAL PUBLISHING, CHAM, vol. 73, no. 4, 1 April 2019 (2019-04-01), Cham , pages 965 - 975, XP093071015, ISSN: 2585-7290, DOI: 10.1007/s11696-018-0634-0
AHER RAVINDRA D.; SUDALAI ARUMUGAM: "Proline catalyzed enantioselective synthesis of (2S,3S)-3-hydroxypipecolic acid and formal synthesis of (+)-swainsonine", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM , NL, vol. 57, no. 19, 15 March 2016 (2016-03-15), Amsterdam , NL , pages 2021 - 2024, XP029512926, ISSN: 0040-4039, DOI: 10.1016/j.tetlet.2016.03.042
BUJARANIPALLI SHESHURAO; DAS SAIBAL: "Stereoselective synthesis of dendrodolide-L", TETRAHEDRON ASYMMETRY, PERGAMON PRESS LTD, OXFORD, GB, vol. 27, no. 6, 1 January 1900 (1900-01-01), OXFORD, GB , pages 254 - 260, XP029461317, ISSN: 0957-4166, DOI: 10.1016/j.tetasy.2016.02.007
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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