Title:
METHOD FOR THE PREPARATION OF CONTROLLED RELEASE FORMULATIONS
Document Type and Number:
WIPO Patent Application WO2005009356
Kind Code:
A3
Abstract:
The methods disclosed herein are of use for the production of controlled release compositions. In particular, the methods provide the contacting of an organic phase containing a bioactive agent and a polymer with an aqueous phase containing an organic ion to create controlled release compositions containing bioactive agents. The present invention also includes controlled release compositions including a polymer, an organic ion and a bioactive agent. The present invention also includes methods of using such controlled release compositions. The usefulness of the present invention is that the methods result in the production of controlled release compositions containing bioactive agent capable of administration in a concentrated low-dose form, having low burst and reduced production of degraded bioactive agent.
Inventors:
GARY P COOK (US)
Application Number:
PCT/US2004/022816
Publication Date:
June 09, 2005
Filing Date:
July 15, 2004
Export Citation:
Assignee:
PR PHARMACEUTICALS (US)
GARY P COOK (US)
GARY P COOK (US)
International Classes:
A61F2/02; A61K9/50; A61K38/095; A61K47/30; A61K; (IPC1-7): A61F2/02; A61K9/50; A61K47/30
Foreign References:
| US6706289B2 | 2004-03-16 |
Other References:
See also references of EP 1651136A4
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