Title:
METHOD FOR PREPARATION OF SGLT-2 INHIBITOR, DAPAGLIFLOZIN PRECURSOR
Document Type and Number:
WIPO Patent Application WO/2020/040433
Kind Code:
A1
Abstract:
The present invention relates to a method for preparation of a dapagliflozin precursor, which is a SGLT-2 inhibitor and, particularly, to a method for preparation of the dapagliflozin precursor, which is the compound of chemical formula 1 disclosed in Korean Patent Application Number 10-2018-0022252. The preparation method of the present invention allows the employment of inexpensive reagents as starting materials and reactants upon reaction, thus lowering the production cost, can exclude a significant portion of the purification procedure for an intermediate, thus reducing production time and cost, and can produce the target compound at improved yield, thus finding advantageous applications in mass production.
Inventors:
SUNG SI-YOUNG (KR)
MIN JONG-PIL (KR)
ULLAPU PUNNA REDDY (KR)
MOK HUI-YEON (KR)
MIN JONG-PIL (KR)
ULLAPU PUNNA REDDY (KR)
MOK HUI-YEON (KR)
Application Number:
PCT/KR2019/009014
Publication Date:
February 27, 2020
Filing Date:
July 22, 2019
Export Citation:
Assignee:
DONG A ST CO LTD (KR)
International Classes:
C07H7/04; C07H1/00
Domestic Patent References:
| WO2018029611A1 | 2018-02-15 | |||
| WO2016041470A1 | 2016-03-24 | |||
| WO2001027128A1 | 2001-04-19 |
Foreign References:
| CN107163092A | 2017-09-15 | |||
| CN104109179A | 2014-10-22 |
Attorney, Agent or Firm:
ROH, Jae-Chull (KR)
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