Title:
A METHOD FOR THE PREPARATION OF STEROID COMPOUNDS
Document Type and Number:
WIPO Patent Application WO1998020151
Kind Code:
A9
Abstract:
Disclosed is a method for the production of an adrenocorticoid steroid represented by general formula (I), wherein R1 and R3 may be H, alkyl, substituted alkyl, silyl, acyl, acyloxy or carbamoyl (and wherein R1 need not be the same as R3), and wherein R2 may be methyl, mono- or disubstituted methyl, substituted alkyl, methyl or substituted alkylhydroxy, silyloxy, alkyloxy, acyl, acyloxy or carbamoyl; the method comprising treatment of a precursor thereof so as to effect the following steps: hydroxylation at the 11 beta position; formation of a double bond between positions 1 and 2; and hydroxylation at position 21.
Inventors:
ROBERTS STANLEY MICHAEL (GB)
EDDOLLS JONATHAN PAUL (GB)
WILLETTS ANDREW JOHN (GB)
ATKINSON ANTHONY (GB)
MURPHY JONATHAN PAUL (GB)
EDDOLLS JONATHAN PAUL (GB)
WILLETTS ANDREW JOHN (GB)
ATKINSON ANTHONY (GB)
MURPHY JONATHAN PAUL (GB)
Application Number:
PCT/GB1997/003003
Publication Date:
June 17, 1999
Filing Date:
October 31, 1997
Export Citation:
Assignee:
DURAMED EUROP LIMITED (GB)
ROBERTS STANLEY MICHAEL (GB)
EDDOLLS JONATHAN PAUL (GB)
WILLETTS ANDREW JOHN (GB)
ATKINSON ANTHONY (GB)
MURPHY JONATHAN PAUL (GB)
ROBERTS STANLEY MICHAEL (GB)
EDDOLLS JONATHAN PAUL (GB)
WILLETTS ANDREW JOHN (GB)
ATKINSON ANTHONY (GB)
MURPHY JONATHAN PAUL (GB)
International Classes:
A46B11/02; C07J5/00; C07J7/00; C12P33/02; (IPC1-7): C12P33/02; C12P33/08; C12P33/12; C07J5/00
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