Title:
METHOD FOR PREPARING 2-SUBSTITUTED ARYL ACETONITRILE COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/216063
Kind Code:
A1
Abstract:
The present invention provides a method for preparing a 2-substituted aryl acetonitrile compound and use thereof. The method prepares the 2-substituted aryl acetonitrile compound by means of a direct reaction under the action of a base with a substituted benzene and a 2-cyanocarboxylate as the starting materials. The reaction formula is as follows. Compared with the prior art, the method provided by the present invention features a high yield and the absence of transition metal catalysts, strong bases, or harsh reaction conditions.
Inventors:
CHEN BANGCHI (CN)
SUN YINWEI (CN)
WANG ZHONGYUAN (CN)
ZHONG YI (CN)
SUN YINWEI (CN)
WANG ZHONGYUAN (CN)
ZHONG YI (CN)
Application Number:
PCT/CN2022/091714
Publication Date:
November 16, 2023
Filing Date:
May 09, 2022
Export Citation:
Assignee:
MAXUNITECH INC (CN)
International Classes:
C07C253/30; C07C255/33
Foreign References:
| EP3670492A1 | 2020-06-24 | |||
| US20200190056A1 | 2020-06-18 | |||
| CN108264450A | 2018-07-10 | |||
| CN105753685A | 2016-07-13 |
Other References:
CHEN YING, XU LANTING, JIANG YONGWEN, MA DAWEI: "Assembly of α‐(Hetero)aryl Nitriles via Copper‐Catalyzed Coupling Reactions with (Hetero)aryl Chlorides and Bromides", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, VERLAG CHEMIE, HOBOKEN, USA, vol. 60, no. 13, 22 March 2021 (2021-03-22), Hoboken, USA, pages 7082 - 7086, XP093106823, ISSN: 1433-7851, DOI: 10.1002/anie.202014638
Attorney, Agent or Firm:
HANGZHOU QIUSHI PATENT OFFICE CO., LTD. (CN)
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