Title:
METHOD FOR PREPARING AQUEOUS SOLUTION CONTAINING CULTURE MEDIUM AND CHELATING AGENT
Document Type and Number:
WIPO Patent Application WO/2012/091023
Kind Code:
A1
Abstract:
Provided are: a preparation method for an aqueous solution that performs stable filtration in a short time and which has high versatility and improved membrane filtration; an aqueous solution prepared using the preparation method; a cell culturing method using the aqueous solution prepared using the preparation method; a production method for a physiologically active substance using the culturing method; the physiologically active substance produced using the aqueous solution production method; a method for membrane filtration of the aqueous solution prepared using the aqueous solution preparation method; a method for improving the membrane filtration of the aqueous solution; and a method for preparing the aqueous solution, membrane filtrating same, culturing cells using the aqueous solution, and producing the physiologically active substance. The present invention pertains to an aqueous solution preparation method characterized by the addition of a chelating agent.
Inventors:
KONNO YOSHINOBU
WAKAMATSU KAIRO
IMAMOTO YASUFUMI
ISHIBASHI JUN
TAKAHASHI KEN
TANAKA HISAYA
WAKAMATSU KAIRO
IMAMOTO YASUFUMI
ISHIBASHI JUN
TAKAHASHI KEN
TANAKA HISAYA
Application Number:
PCT/JP2011/080236
Publication Date:
July 05, 2012
Filing Date:
December 27, 2011
Export Citation:
Assignee:
KYOWA HAKKO KIRIN CO LTD (JP)
KONNO YOSHINOBU
WAKAMATSU KAIRO
IMAMOTO YASUFUMI
ISHIBASHI JUN
TAKAHASHI KEN
TANAKA HISAYA
KONNO YOSHINOBU
WAKAMATSU KAIRO
IMAMOTO YASUFUMI
ISHIBASHI JUN
TAKAHASHI KEN
TANAKA HISAYA
International Classes:
C12N5/071; B01D61/14; C12N1/00; C12P1/00; C12P21/02; C12P21/08
Domestic Patent References:
| WO2010036774A1 | 2010-04-01 | |||
| WO2010036760A1 | 2010-04-01 | |||
| WO2005017130A2 | 2005-02-24 | |||
| WO1994023021A1 | 1994-10-13 | |||
| WO1996030046A1 | 1996-10-03 | |||
| WO1996040210A1 | 1996-12-19 | |||
| WO1998051793A1 | 1998-11-19 | |||
| WO2010008075A1 | 2010-01-21 |
Foreign References:
| JP2006500931A | 2006-01-12 | |||
| JPH07506492A | 1995-07-20 | |||
| JP2003250533A | 2003-09-09 | |||
| JP2000217455A | 2000-08-08 | |||
| US6855544B1 | 2005-02-15 | |||
| JPH0322979A | 1991-01-31 | |||
| JPH02227075A | 1990-09-10 | |||
| JPH05336963A | 1993-12-21 | |||
| US5725856A | 1998-03-10 | |||
| US5736137A | 1998-04-07 |
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THE JOURNAL OF RHEUMATOLOGY, vol. 33, November 2006 (2006-11-01), pages 2124 - 2131
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CANCER, vol. 88, 2000, pages 2909
PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 9911
J. BIOL. CHEM., vol. 265, 1990, pages 16455
J. NEUROSCI. RES., vol. 40, 1995, pages 647
J. UROLOGY, vol. 160, 1998, pages 2396
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ONCOGENE, vol. 19, 2000, pages 2138
CURR. OPIN. ONCOL., vol. 10, 1998, pages 548
CANCER RES., vol. 55, no. 23, 1995, pages 5935S - 5945S
IMMUNOL. REV., vol. 127, 1992, pages 5
MOLECULAR IMMUNOL., vol. 31, 1994, pages 371
CYTOKINE, vol. 3, 1991, pages 562
J. IMMUNOL. METHODS, vol. 217, 1998, pages 41
HYBRIDOMA, vol. 13, 1994, pages 183
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NATURE, vol. 400, 1999, pages 776
PERI ET AL., J. IMMUNOL. METH., vol. 174, 1994, pages 249
J. EXP. MED., vol. 186, 1997, pages 1373
J. IMMUNOL., vol. 152, 1994, pages 2968
SCIENCE, vol. 253, 1991, pages 1129
J. BIOL. CHEM., vol. 272, 1997, pages 17400
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BIOPHARM, vol. 46, September 2006 (2006-09-01)
See also references of EP 2660315A4
NATURE, vol. 339, 1989, pages 487 - 488
THE JOURNAL OF RHEUMATOLOGY, vol. 33, November 2006 (2006-11-01), pages 2124 - 2131
"Filter Sterilization of Samples (1- 100 mL) in Sterile Acrodisc (Registered trademark) Syringe Filters.5.3", 15 November 2010, PALL CORPORATION
"Book of Abstracts of The 23rd Annual and International Meeting of the Japanese Association for Animal Cell Technology", September 2010, pages: 127
JOURNAL OF DENTAL RESEARCH, vol. 46, no. 3, May 1967 (1967-05-01), pages 514 - 521
THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, vol. 199, 1967, pages 519
SCIENCE, vol. 122, 1952, pages 501
VIROLOGY, vol. 8, 1959, pages 396
PROCEEDING OF THE SOCIETY FOR THE BIOLOGICAL MEDICINE, vol. 73, 1950, pages 1
PROC. NATL. ACAD. SCI. USA, vol. 53, 1965, pages 288
J. EXPERIMENTAL MEDICINE, vol. 147, 1978, pages 923
JOURNAL OF EXPERIMENTAL MEDICINE, vol. 108, 1958, pages 945
PROC. NATL. ACAD. SCI. USA, vol. 60, 1968, pages 1275
GENETICS, vol. 55, 1968, pages 513
CHROMOSOMA, vol. 41, 1973, pages 129
METHODS IN CELL SCIENCE, vol. 18, 1996, pages 115
RADIATION RESEARCH, vol. 148, 1997, pages 260
PROC. NATL. ACAD. SCI, USA, vol. 77, 1980, pages 4216
PROC. NATL. ACAD. SCI., vol. 60, 1968, pages 1275
CELL, vol. 6, 1975, pages 121
MOLECULAR CELLGENETICS, APPENDIX I, II, pages 883 - 900
PROC. NATL. ACAD. SCI. USA, vol. 77, 1980, pages 4216
CYTOTECHNOLOGY, vol. 3, 1990, pages 133
NATURE, vol. 329, 1987, pages 840
J. BIOCHEM., vol. 101, 1987, pages 1307
PROC. NATL. ACAD. SCI. USA, vol. 84, 1987, pages 7413
VIROLOGY, vol. 52, 1973, pages 456
PAULSON ET AL., JBIOL.CHEM., vol. 264, 1989, pages 17619
LOWE ET AL., PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 8227
GENES DEVELOP., vol. 4, 1990, pages 1288
J. BIOL. CHEM., vol. 252, 1977, pages 5558
NATURE, vol. 369, 1994, pages 533
J. BIOL. CHEM., vol. 258, 1983, pages 9017
J. EXP. MED., vol. 173, 1992, pages 269
J. BIOL. CHEM., vol. 252, 1977, pages 1998
SCIENCE, vol. 193, 1976, pages 1007
J. LEUC. BIOL., vol. 55, 1994, pages 280
PROC. NATL. ACAD. SCI. USA, vol. 97, 2000, pages 722
ANTICANCER RES., vol. 13, 1993, pages 331
CANCER IMMUNOL. IMMUNOTHER., vol. 36, 1993, pages 260
CANCER RES., vol. 54, 1994, pages 1511
PROC. NATL. ACAD. SCI. USA, vol. 89, 1992, pages 4285
BRITISH J. CANCER, vol. 83, 2000, pages 493
MOLECULAR IMMUNOL., vol. 36, 1999, pages 387
CANCER, vol. 88, 2000, pages 2909
PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 9911
J. BIOL. CHEM., vol. 265, 1990, pages 16455
J. NEUROSCI. RES., vol. 40, 1995, pages 647
J. UROLOGY, vol. 160, 1998, pages 2396
CANCER RES., vol. 57, 1997, pages 4593
ONCOGENE, vol. 19, 2000, pages 2138
CURR. OPIN. ONCOL., vol. 10, 1998, pages 548
CANCER RES., vol. 55, no. 23, 1995, pages 5935S - 5945S
IMMUNOL. REV., vol. 127, 1992, pages 5
MOLECULAR IMMUNOL., vol. 31, 1994, pages 371
CYTOKINE, vol. 3, 1991, pages 562
J. IMMUNOL. METHODS, vol. 217, 1998, pages 41
HYBRIDOMA, vol. 13, 1994, pages 183
MOLECULAR PHARMACOL., vol. 58, 2000, pages 237
NATURE, vol. 400, 1999, pages 776
PERI ET AL., J. IMMUNOL. METH., vol. 174, 1994, pages 249
J. EXP. MED., vol. 186, 1997, pages 1373
J. IMMUNOL., vol. 152, 1994, pages 2968
SCIENCE, vol. 253, 1991, pages 1129
J. BIOL. CHEM., vol. 272, 1997, pages 17400
CIRCULATION, vol. 101, 2000, pages 1158
STRUCTURE, vol. 8, 2000, pages 385
J. RHEUMATOLOGY, vol. 25, 1998, pages 2065
J. CLIN. MICROBIOL., vol. 37, 1999, pages 396
BIOPHARM, vol. 46, September 2006 (2006-09-01)
See also references of EP 2660315A4
Attorney, Agent or Firm:
OGURI Shohei et al. (JP)
Shohei Oguri (JP)
Shohei Oguri (JP)
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