Title:
METHOD FOR PREPARING BIONIC COLLAGEN AQUEOUS SOLUTION AND USE METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/089295
Kind Code:
A1
Abstract:
The present invention relates to the field of biological materials, particularly to a bionic collagen aqueous solution, and a preparation method therefor and a use method thereof. According to the invention, by adding simulated body fluid components, the ion components and ion strength of the collagen aqueous solution are regulated, the pH value is further regulated, and a tissue microenvironment is simulated; and by adding the connecting molecules, the binding of collagen molecules to tissues is improved, and the biocompatibility of the collagen aqueous solution is enhanced. The concentration of the collagen aqueous solution is greater than 0.1 wt.% and less than or equal to 10 wt.%, and the collagen aqueous solution can be used to cover the surface of the skin in the form of a dressing, and can also be applied to the body in an injected manner. The bionic collagen aqueous solution of the present invention simulates some characteristics of pre-repaired tissue, has a good biocompatibility, and delays the degradation of collagen molecules during use, which is beneficial for tissue repair and regeneration.
Inventors:
DU MINGCHUN (CN)
Application Number:
PCT/CN2021/125224
Publication Date:
May 05, 2022
Filing Date:
October 21, 2021
Export Citation:
Assignee:
DU MINGCHUN (CN)
International Classes:
A61L27/24; A61K8/19; A61K8/24; A61K8/49; A61K8/65; A61L15/32; A61L26/00; A61L27/50; A61L27/52; A61L27/58; A61Q19/00; A61Q19/08
Foreign References:
| CN112354013A | 2021-02-12 | |||
| CN112402289A | 2021-02-26 | |||
| CN107308494A | 2017-11-03 | |||
| CN101934092A | 2011-01-05 | |||
| CN106913912A | 2017-07-04 |
Other References:
See also references of EP 4169540A4
Attorney, Agent or Firm:
BEIJING BICREATION INTELLECTUAL PROPERTY LLC. (CN)
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