Title:
METHOD FOR PREPARING COCRYSTAL OF L-PYROGLUTAMIC ACID AND GLUCOPYRANOSYL DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2022/204907
Kind Code:
A1
Abstract:
Provided is a method for preparing a cocrystal of L-pyroglutamic acid and a glucopyranosyl derivative, which can be used as a sodium-dependent glucose transporter (SGLT) inhibitor. The method is stable and controllable, so the target cocrystal can be obtained stably in high-yield and applied to scale-up process.
Inventors:
GU ZHENG (CN)
CHEN DAOQIAN (CN)
WU WUYONG (CN)
YE HUIQING (CN)
LI JIANHAO (CN)
LI ZHENG (CN)
ZHANG ZONGYUAN (CN)
NIU SHIJIE (CN)
WU YUSHENG (CN)
CHEN DAOQIAN (CN)
WU WUYONG (CN)
YE HUIQING (CN)
LI JIANHAO (CN)
LI ZHENG (CN)
ZHANG ZONGYUAN (CN)
NIU SHIJIE (CN)
WU YUSHENG (CN)
Application Number:
PCT/CN2021/083791
Publication Date:
October 06, 2022
Filing Date:
March 30, 2021
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D207/28; A61K31/357; A61K31/7048; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P13/12; C07D493/08; C07H1/00; C07H9/04
Domestic Patent References:
| WO2017088839A1 | 2017-06-01 | |||
| WO2015027963A1 | 2015-03-05 |
Foreign References:
| CN108239123A | 2018-07-03 | |||
| CN106083943A | 2016-11-09 | |||
| CN104513283A | 2015-04-15 |
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