Title:
METHOD FOR PREPARING COUPLED BODY OF LEAVING GROUP-CONTAINING ORGANIC COMPOUND AND ORGANOSILICON COMPOUND
Document Type and Number:
WIPO Patent Application WO/2019/159596
Kind Code:
A1
Abstract:
Provided is a method for preparing a coupled body represented by general formula (3), the coupled body being obtained by reacting a compound represented by general formula (1) and a compound represented by general formula (2) in the presence of an alcohol solvent, an inorganic base, and a palladium catalyst, the alcohol solvent having a site in which two adjacent carbon atoms each have a hydroxyl group. Ar1-X ··· (1) Ar2-Si(OR)3 ··· (2) Ar1-Ar2 ··· (3) [In the formulae, Ar1 represents an aryl group, etc., which may be substituted; X represents a leaving group such as a bromine atom; Ar2 represents an aryl group, etc., which may be substituted; and R represents an alkyl group having 1-5 carbon atoms.]
Inventors:
UOZUMI YASUHIRO (JP)
HAMASAKA GO (JP)
ICHII SHUN (JP)
HAMASAKA GO (JP)
ICHII SHUN (JP)
Application Number:
PCT/JP2019/001343
Publication Date:
August 22, 2019
Filing Date:
January 17, 2019
Export Citation:
Assignee:
INTER UNIV RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCES (JP)
International Classes:
C07B37/04; C07C1/32; C07C15/14; C07C15/20; C07C15/27; C07C15/44; C07C15/58; C07C17/263; C07C25/18; C07C37/18; C07C39/17; C07C41/30; C07C43/205; C07C45/68; C07C47/546; C07C49/784; C07C51/367; C07C65/26; C07C67/343; C07C69/76; C07C201/12; C07C205/06; C07C209/68; C07C211/55; C07C231/12; C07C233/65; C07C253/30; C07C255/54; C07D209/08; C07D213/64; C07D215/04; C07D231/12; C07D239/42; C07D295/023; C07D295/033; C07D307/79; C07D317/50; C07D333/08; C07B61/00
Other References:
BLASZCZYK, IZABELA ET AL.: "Suzuki-Miyaura and Hiyama reactions catalyzed by orthopalladated triarylphosphite complexes", TETRAHEDRON, vol. 66, 2010, pages 9502 - 9507, XP027471728
BLASZCZYK, IZABELA ET AL.: "Orthometallated palladium trimers in C-C coupling reactions", JOURNAL OF ORGANOMETALLIC CHEMISTRY, vol. 710, 2012, pages 44 - 52, XP028417338
OMOTE, MASAAKI ET AL.: "Simple synthesis of beta -trifluoromethylstyrenes using (E)-trimethyl-(3,3,3-trifluoroprop-1-enyl)silane", ORGANIC LETTERS, vol. 14, no. 9, 2012, pages 2286 - 2289
HAMASAKA, GO ET AL.: "A palladium NNC-pincer complex: an efficient catalyst for allylic arylation at parts per billion levels", CHEMCOMMUN., vol. 51, 2015, pages 3886 - 3888, XP055636011
BLASZCZYK, IZABELA ET AL.: "Orthometallated palladium trimers in C-C coupling reactions", JOURNAL OF ORGANOMETALLIC CHEMISTRY, vol. 710, 2012, pages 44 - 52, XP028417338
OMOTE, MASAAKI ET AL.: "Simple synthesis of beta -trifluoromethylstyrenes using (E)-trimethyl-(3,3,3-trifluoroprop-1-enyl)silane", ORGANIC LETTERS, vol. 14, no. 9, 2012, pages 2286 - 2289
HAMASAKA, GO ET AL.: "A palladium NNC-pincer complex: an efficient catalyst for allylic arylation at parts per billion levels", CHEMCOMMUN., vol. 51, 2015, pages 3886 - 3888, XP055636011
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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