Title:
METHOD FOR PREPARING ESTER COMPOUND BASED ON ECO-FRIENDLY AND HIGH-EFFICIENCY ESTERIFICATION REACTION USING SALT ION-EXCHANGE METHOD, AND COMPOUND THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/097813
Kind Code:
A1
Abstract:
The present invention relates to an eco-friendly and highly efficient method for preparing an ester compound based on an esterification reaction using a salt ion-exchange method, and an ester compound thereof. In conventional esterification reactions, since hydrolysis proceeds as a reverse reaction with water, and thus the yield of ester is not good, or, as a method for avoiding hydrolysis, hydrochloric acid gas is continuously supplied or thionyl chloride, which is a hazardous substance, is used, esterification reactions have limitations in terms of environment and cost. Accordingly, in the present invention, hydrochloric acid gas is continuously supplied by using a salt ion-exchange method, and magnesium sulfate acts as a dehydrating agent and removes water produced in the esterification reaction, thereby reducing the progress of a reverse reaction of hydrolysis and increasing the conversion rate of a desired ester compound. In addition, since reactants are cheap and the product thereof also has low toxicity and is easy to handle, a more efficient reaction is enabled.
Inventors:
LEE SEONG EUN (KR)
KIM GAB YONG (KR)
KIM GAB YONG (KR)
Application Number:
PCT/KR2020/016740
Publication Date:
May 12, 2022
Filing Date:
November 24, 2020
Export Citation:
Assignee:
WOODWARD BIO CORP (KR)
International Classes:
C07C67/30; C07C67/39; C07C67/48; C07C69/013; C07C69/24; C07C69/612; C07C277/08; C07C279/14
Foreign References:
| KR20200108764A | 2020-09-21 | |||
| US8278478B2 | 2012-10-02 | |||
| EP0552541A1 | 1993-07-28 | |||
| KR101141856B1 | 2012-05-08 | |||
| JPH03223233A | 1991-10-02 |
Other References:
See also references of EP 4015499A4
Attorney, Agent or Firm:
OLIM IP& LAW FIRM (KR)
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