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Title:
METHOD FOR PREPARING FIBER-BASED DRESSING HAVING DIRECTIONAL EXUDATE-GUIDING FUNCTION
Document Type and Number:
WIPO Patent Application WO/2024/011901
Kind Code:
A1
Abstract:
A method for preparing a fiber-based dressing having a directional exudate-guiding function. The method comprises: step I, respectively preparing a spinning solution of a hydrophobic layer, a spinning solution of a transition layer A, a spinning solution of a transition layer B, and a spinning solution of a transition layer C, wherein the spinning solutions have different hydrophobicity; step II, sequentially forming, by means of electrospinning, the transition layer C, the transition layer B, the transition layer A and the hydrophobic layer on a surface of a cotton fabric, so as to obtain a composite membrane; step III, forming, by means of a mold, hemispherical bulges and tapered channels on a surface of the composite membrane; step IV, cutting the composite membrane obtained in step III into an A-type composite membrane having an exudate guiding strip at a side edge, and cutting the composite membrane obtained in step II into a B-type composite membrane, which has no exudate guiding strip and matches the A-type composite membrane in terms of size; and step V, fitting the A-type composite membrane to the B-type composite membrane, and sealing the periphery thereof to obtain a wound dressing. The fiber-based dressing is provided with a plurality of transition layers having gradient wettability, such that a wound exudate can be directionally guided out and collected; moreover, the hemispherical bulges and the tapered channels are constructed on a surface of the dressing, such that the exudate guiding efficiency can be regulated by means of an external force.

Inventors:
WU JINDAN (CN)
QI DONGMING (CN)
LIU LEI (CN)
GAO YUJIE (CN)
QIU ZHIYE (CN)
Application Number:
PCT/CN2023/075554
Publication Date:
January 18, 2024
Filing Date:
February 11, 2023
Export Citation:
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Assignee:
UNIV ZHEJIANG SCIENCE & TECH (CN)
International Classes:
A61F13/02; A61L15/18
Domestic Patent References:
WO2017148099A12017-09-08
WO2018090925A12018-05-24
Foreign References:
CN115137557A2022-10-04
CN115025273A2022-09-09
CN110269749A2019-09-24
CN107059251A2017-08-18
CN107106722A2017-08-29
CN108175573A2018-06-19
CN109908392A2019-06-21
CN110820172A2020-02-21
CN111228040A2020-06-05
CN112853739A2021-05-28
CN113368295A2021-09-10
CN113699696A2021-11-26
KR20100004141A2010-01-13
US20080255492A12008-10-16
US20130150763A12013-06-13
Attorney, Agent or Firm:
ZHEJIANG YONGHANG LIANKE PATENT AGENCY CO., LTD. (CN)
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