Title:
METHOD FOR PREPARING OXAZOLIDINONE INTERMEDIATE
Document Type and Number:
WIPO Patent Application WO/2017/076293
Kind Code:
A1
Abstract:
The invention relates to a method for preparing an oxazolidinone intermediate. Specifically, a synthesis procedure for the intermediate comprises: directly performing a "one-pot" reaction on a compound I, a compound J or a compound L without performing isolation, wherein a salt of a compound K is selected from a hydrochloride, sulfate, malate, tartarate, p-toluenesulfonate or lactate, and wherein the symbol * in a compound indicates an atom of an R-type chirality or an S-type chirality or a racemate thereof.
Inventors:
LI SIYUAN (CN)
GUI SHAOXIAO (CN)
WANG GENLIANG (CN)
ZHANG JICHENG (CN)
HUANG LUNING (CN)
TAO ANPING (CN)
GU HONG (CN)
GUI SHAOXIAO (CN)
WANG GENLIANG (CN)
ZHANG JICHENG (CN)
HUANG LUNING (CN)
TAO ANPING (CN)
GU HONG (CN)
Application Number:
PCT/CN2016/104360
Publication Date:
May 11, 2017
Filing Date:
November 02, 2016
Export Citation:
Assignee:
ZHEJIANG HUAHAI PHARM CO LTD (CN)
SHANGHAI AOBO PHARMTECH INC LTD (CN)
SHANGHAI AOBO PHARMTECH INC LTD (CN)
International Classes:
C07D413/14; C07C213/00; C07C217/48; C07C231/10; C07C235/78; C07D263/20
Foreign References:
| EP1008590A1 | 2000-06-14 | |||
| CN104496979A | 2015-04-08 | |||
| CN103304594A | 2013-09-18 |
Other References:
KAMAL, A. ET AL.: "New Chemoenzymatic Pathway for beta-adrenergic Blocking Agents", TETRAHEDRON ASYMMETRY, vol. 16, 31 December 2005 (2005-12-31), pages 1485 - 1494, XP 027675792
DATABASE Chemical Abstract 31 December 1988 (1988-12-31), ANONYMOUS, XP 055543793, retrieved from STN Database accession no. 113681-80-4
VITI, G. ET AL.: "New Antagonists of Platelet-Activating Factor Containing 2-Oxazolidinone or 2-MorpholinoneEuropean", JOURNAL OF MEDICINAL CHEMISTRY, vol. 29, no. 5, 31 December 1994 (1994-12-31), pages 401 - 406, XP 023870432, DOI: doi:10.1016/0223-5234(94)90066-3
ZHANG, HUIZHEN ET AL.: "Recent Advances in Syntheses of Oxazole Compounds", CHINESE JOURNAL OF ORGANIC CHEMISTRY, vol. 31, no. 12, 31 December 2011 (2011-12-31), pages 1963 - 1976, XP 009510494
See also references of EP 3372597A4
DATABASE Chemical Abstract 31 December 1988 (1988-12-31), ANONYMOUS, XP 055543793, retrieved from STN Database accession no. 113681-80-4
VITI, G. ET AL.: "New Antagonists of Platelet-Activating Factor Containing 2-Oxazolidinone or 2-MorpholinoneEuropean", JOURNAL OF MEDICINAL CHEMISTRY, vol. 29, no. 5, 31 December 1994 (1994-12-31), pages 401 - 406, XP 023870432, DOI: doi:10.1016/0223-5234(94)90066-3
ZHANG, HUIZHEN ET AL.: "Recent Advances in Syntheses of Oxazole Compounds", CHINESE JOURNAL OF ORGANIC CHEMISTRY, vol. 31, no. 12, 31 December 2011 (2011-12-31), pages 1963 - 1976, XP 009510494
See also references of EP 3372597A4
Attorney, Agent or Firm:
PATENTSINO IP FIRM (CN)
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