Title:
METHOD FOR PREPARING PROTEIN CAGE, AND IN SITU METHOD FOR PREPARING HYDROPHOBIC ADDITIVE-SUPPORTED CORE-SHELL STRUCTURED POLYMER-PROTEIN PARTICLES
Document Type and Number:
WIPO Patent Application WO/2014/148713
Kind Code:
A1
Abstract:
A method for preparing a protein cage according to the present invention comprises: a first step of preparing an amphiphilic polymer comprising a hydrophobic first polymer and a hydrophilic first functional group; a second step of preparing a hydrophilic protein comprising a second functional group binding to the first functional group; a third step of forming an amphiphilic polymer-protein hybrid by the binding of the first functional group and the second functional group, and forming core-shell structured particles comprising a protein shell and an amphiphilic polymer core by the self-assembly of the amphiphilic polymer in a hydrophilic solvent; and a fourth step of removing a part or all of a hydrophobic polymer of the core part from the core-shell structured particles.
Inventors:
PAIK HYUN JONG (KR)
SONG JAE KWANG (KR)
AN SEONG SOO (KR)
LEE CHAE YEON (KR)
JEONG JONG HWA (KR)
KADIR MOHAMMAD ABDUL (KR)
LEE TAE HEON (KR)
SONG JAE KWANG (KR)
AN SEONG SOO (KR)
LEE CHAE YEON (KR)
JEONG JONG HWA (KR)
KADIR MOHAMMAD ABDUL (KR)
LEE TAE HEON (KR)
Application Number:
PCT/KR2013/009120
Publication Date:
September 25, 2014
Filing Date:
October 11, 2013
Export Citation:
Assignee:
PUSAN NAT UNIV IND COOP FOUND (KR)
KOREA RES INST CHEM TECH (KR)
UNIV GACHON IND ACAD COOP FOUND (KR)
KOREA RES INST CHEM TECH (KR)
UNIV GACHON IND ACAD COOP FOUND (KR)
International Classes:
B82B1/00; C08H1/00
Foreign References:
| US20120219600A1 | 2012-08-30 | |||
| KR20070099767A | 2007-10-10 | |||
| KR20080030555A | 2008-04-04 | |||
| US20020187197A1 | 2002-12-12 | |||
| US20120141591A1 | 2012-06-07 |
Attorney, Agent or Firm:
SON, MIN (KR)
손민 (KR)
손민 (KR)
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