Title:
METHOD FOR PREPARING SAMPLE FOR ANALYSIS AND METHOD FOR ANALYZING SAME
Document Type and Number:
WIPO Patent Application WO/2023/243136
Kind Code:
A1
Abstract:
Provided is a method for analyzing an O-linked sugar chain that has been undergone sialic acid linkage-specific modification, the method comprising: a modification step for adding a modifier, which performs sialic acid linkage-specific modification on the O-linked sugar chain, to a sample containing a glycoprotein to which the O-linked sugar chain is linked; a release step for releasing, from the glycoprotein, the O-linked sugar chain that has been undergone the sialic acid linkage-specific modification; and an analysis step for analyzing the released O-linked sugar chain that has been undergone the sialic acid linkage-specific modification.
Inventors:
NISHIKAZE TAKASHI (JP)
FURUKAWA JUN-ICHI (JP)
HANAMATSU HISATOSHI (JP)
FURUKAWA JUN-ICHI (JP)
HANAMATSU HISATOSHI (JP)
Application Number:
PCT/JP2023/003906
Publication Date:
December 21, 2023
Filing Date:
February 07, 2023
Export Citation:
Assignee:
SHIMADZU CORP (JP)
International Classes:
G01N33/50; C07K1/30; G01N27/447; G01N27/62; G01N30/06; G01N30/88; G01N33/66
Domestic Patent References:
| WO2021010221A1 | 2021-01-21 |
Foreign References:
| JP2020030181A | 2020-02-27 | |||
| JP6852397B2 | 2021-03-31 | |||
| JP2016194500A | 2016-11-17 | |||
| JP2019152475A | 2019-09-12 | |||
| JP6368502B2 | 2018-08-01 |
Other References:
TSUMOTO, HIROKI: "Development of a method to analyze =-linked glycopeptides using sialic acid linkage-specific derivatization", 68TH ANNUAL CONFERENCE ON MASS SPECTROMETRY; MASS SPECTROMETRY GENERAL DISCUSSION CONFERENCE; 2020/05/11-13, MASS SPECTROMETRY SOCIETY OF JAPAN, JP, vol. 68, 1 May 2020 (2020-05-01) - 13 May 2020 (2020-05-13), JP, pages 52, XP009551769
NISHIKAZE, TAKASHI: "Development and application of SialoCapper-ID Kit - A new derivatization tool for glycan analysis using mass spectrometry-", BUNSEKI, NIHON BUNSEKI KAGAKUKAI, TOKYO, JP, no. 10, 5 October 2021 (2021-10-05), JP , pages 570 - 576, XP009551734, ISSN: 0386-2178
FUNAOKA, SOHEI: "Biopharmaceutical Manufacturing Technology Series “BlotGlyco Kit” sample pretreatment method for glycan analysis of glycoprotein biopharmaceuticals", PHARM TECH JAPAN, JIHO, INC., JP, vol. 28, no. 9, 1 July 2012 (2012-07-01), JP , pages 1847 - 1853, XP009551771, ISSN: 0910-4739
HANAMATSU, HISATOSHI: "The future brought by Human Glycome: Development elements of primary structure analysis technology for sugar chains", JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, NIPPON SEIKAGAKKAI, TOKYO, JP, vol. 92, no. 3, 25 June 2020 (2020-06-25), JP , pages 360 - 368, XP009551758, ISSN: 0037-1017
HIROKI TSUMOTO, TAKASHI NISHIKAZE, SADANORI SEKIYA, SHINICHI IWAMOTO, KOICHI TANAKA, YURI MIURA, TAMAO ENDO: "P35C: Development of glycopeptide analysis method using sialic acid binding mode-specific derivatization method", PROGRAMS AND ABSTRACTS OF ANNUAL MEETING OF JAPANESE PROTEOMICS SOCIETY; JULY 24-27, 2019, JAPANESE PROTEOMICS SOCIETY, JP, vol. 2019, 1 January 2019 (2019-01-01) - 27 July 2019 (2019-07-27), JP, pages 210, XP009551777, DOI: 10.14889/jhupo.2019.0.210.0
T. NISHIKAZE, S. SEKIYA, S. JWAMOTO: "1P-28 Linkage-specific derivatization of sialic acids on glycopeptides", ANNUAL CONFERENCE ON MASS SPECTROMETRY, BOOK OF ABSTRACTS, vol. 65, 1 May 2017 (2017-05-01), pages 66, XP009551763
HIROKI TSUMOTO, TAKASHI NISHIKAZE, KEITARO UMEZAWA, KYOJIRO KAWAKAMI, YOSHIHIRO HAYAKAWA, YURI MIURA, TAMAO ENDO: "P-064: Analysis of glycopeptides in human plasma proteins using sialic acid linkage-specific alkylamidation", 40TH ANNUAL MEETING OF JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH; OCTOBER 27-29, 2021, vol. 40, 15 October 2021 (2021-10-15), JP, pages 155, XP009551755
HANAMATSU, HI SATOSHI: "Development of structural isomer discrimination method by linkage specific sialic acid derivatization", ABSTRACTS OF THE ANNUAL MEETING OF THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH, vol. 40, 15 October 2021 (2021-10-15), pages 59 - 60, XP009551756
NISHIKAZE, TAKASHI: "Towards highly sensitive and detailed structural analysis of glycan modifications using MALDI-MS", ANNUAL REPORT OF THE NOGUCHI INSTITUTE, NOGUCHI INSTITUTE, JP, no. 61, 1 October 2018 (2018-10-01), JP , pages 4 - 16, XP009551778, ISSN: 0369-5131
NISHIKAZE, TAKASHI: "Development and application of SialoCapper-ID Kit - A new derivatization tool for glycan analysis using mass spectrometry-", BUNSEKI, NIHON BUNSEKI KAGAKUKAI, TOKYO, JP, no. 10, 5 October 2021 (2021-10-05), JP , pages 570 - 576, XP009551734, ISSN: 0386-2178
FUNAOKA, SOHEI: "Biopharmaceutical Manufacturing Technology Series “BlotGlyco Kit” sample pretreatment method for glycan analysis of glycoprotein biopharmaceuticals", PHARM TECH JAPAN, JIHO, INC., JP, vol. 28, no. 9, 1 July 2012 (2012-07-01), JP , pages 1847 - 1853, XP009551771, ISSN: 0910-4739
HANAMATSU, HISATOSHI: "The future brought by Human Glycome: Development elements of primary structure analysis technology for sugar chains", JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, NIPPON SEIKAGAKKAI, TOKYO, JP, vol. 92, no. 3, 25 June 2020 (2020-06-25), JP , pages 360 - 368, XP009551758, ISSN: 0037-1017
HIROKI TSUMOTO, TAKASHI NISHIKAZE, SADANORI SEKIYA, SHINICHI IWAMOTO, KOICHI TANAKA, YURI MIURA, TAMAO ENDO: "P35C: Development of glycopeptide analysis method using sialic acid binding mode-specific derivatization method", PROGRAMS AND ABSTRACTS OF ANNUAL MEETING OF JAPANESE PROTEOMICS SOCIETY; JULY 24-27, 2019, JAPANESE PROTEOMICS SOCIETY, JP, vol. 2019, 1 January 2019 (2019-01-01) - 27 July 2019 (2019-07-27), JP, pages 210, XP009551777, DOI: 10.14889/jhupo.2019.0.210.0
T. NISHIKAZE, S. SEKIYA, S. JWAMOTO: "1P-28 Linkage-specific derivatization of sialic acids on glycopeptides", ANNUAL CONFERENCE ON MASS SPECTROMETRY, BOOK OF ABSTRACTS, vol. 65, 1 May 2017 (2017-05-01), pages 66, XP009551763
HIROKI TSUMOTO, TAKASHI NISHIKAZE, KEITARO UMEZAWA, KYOJIRO KAWAKAMI, YOSHIHIRO HAYAKAWA, YURI MIURA, TAMAO ENDO: "P-064: Analysis of glycopeptides in human plasma proteins using sialic acid linkage-specific alkylamidation", 40TH ANNUAL MEETING OF JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH; OCTOBER 27-29, 2021, vol. 40, 15 October 2021 (2021-10-15), JP, pages 155, XP009551755
HANAMATSU, HI SATOSHI: "Development of structural isomer discrimination method by linkage specific sialic acid derivatization", ABSTRACTS OF THE ANNUAL MEETING OF THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH, vol. 40, 15 October 2021 (2021-10-15), pages 59 - 60, XP009551756
NISHIKAZE, TAKASHI: "Towards highly sensitive and detailed structural analysis of glycan modifications using MALDI-MS", ANNUAL REPORT OF THE NOGUCHI INSTITUTE, NOGUCHI INSTITUTE, JP, no. 61, 1 October 2018 (2018-10-01), JP , pages 4 - 16, XP009551778, ISSN: 0369-5131
Attorney, Agent or Firm:
FUKAMI PATENT OFFICE, P.C. (JP)
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