Title:
METHOD FOR PREPARING SOLID PHOTONIC CRYSTAL IPN COMPOSITE FUNCTIONALIZED WITH ENZYME, PHOTONIC CRYSTAL IPN COMPOSITE PREPARED THEREBY, AND BIOSENSOR USING SAME
Document Type and Number:
WIPO Patent Application WO/2019/168292
Kind Code:
A1
Abstract:
The present invention relates to: a method for preparing a solid photonic crystal IPN composite functionalized with an enzyme, the method allowing a PAA hydrogel to penetrate a solid spiral photonic crystal structure and binding an enzyme thereto, thereby allowing the solid photonic crystal IPN composite to exhibit a color change by inducing the contraction and expansion of the PAA hydrogel through a pH change caused by an enzymatic reaction; an IPN composite prepared thereby; and a biosensor using same. The present invention comprises the steps of: (1) mixing and curing an unreactive chiral dopant and a reactive nematic mesogen, and then removing the chiral dopant while maintaining a spiral structure, thereby preparing a solid spiral photonic crystal structure; (2) allowing a PAA hydrogel to penetrate the inner space of the photonic crystal structure, and then curing the same, thereby forming a composite having an IPN structure; and (3) binding an enzyme to the composite having an IPN structure.
Inventors:
PARK SOO YOUNG (KR)
NOH KYUNG GYU (KR)
NOH KYUNG GYU (KR)
Application Number:
PCT/KR2019/002039
Publication Date:
September 06, 2019
Filing Date:
February 20, 2019
Export Citation:
Assignee:
KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR)
International Classes:
C08F20/06; C12Q1/58; C08F283/12; C08J3/075; C09K19/02; C12N11/04; G01N21/31; G01N33/573; G01N33/62
Foreign References:
| KR101825597B1 | 2018-02-05 | |||
| KR20040066159A | 2004-07-23 |
Other References:
STUMPEL, J. E. ET AL.: "Stimuli-responsive materials based on interpenetrating polymer liquid crystal hydrogels", ADVANCED FUNCTIONAL MATERIALS, vol. 25, no. 22, 17 April 2015 (2015-04-17), pages 3314 - 3320, XP055635286
KHAN, M. ET AL.: "Real-time liquid crystal-based biosensor for urea detection", ANALYTICAL METHODS, vol. 6, no. 15, 2 June 2014 (2014-06-02), pages 5753 - 5759, XP055635293
NOH, K.G. ET AL.: "Smart molecular-spring photonic droplets", MATERIALS HORIZONS, vol. 4, no. 4, 28 April 2017 (2017-04-28), pages 633 - 640, XP055635300
KHAN, M. ET AL.: "Real-time liquid crystal-based biosensor for urea detection", ANALYTICAL METHODS, vol. 6, no. 15, 2 June 2014 (2014-06-02), pages 5753 - 5759, XP055635293
NOH, K.G. ET AL.: "Smart molecular-spring photonic droplets", MATERIALS HORIZONS, vol. 4, no. 4, 28 April 2017 (2017-04-28), pages 633 - 640, XP055635300
Attorney, Agent or Firm:
KIM, Sung Hyun (KR)
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