Title:
METHOD FOR PRODUCING 2-HETEROARYLPYRIDINE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2023/090344
Kind Code:
A1
Abstract:
The present invention provides a method for producing a compound represented by formula (3) (in the formula, Q, R1, and R2 represent the same as in formula (1) and formula (2)) that includes chemically reacting a compound represented by formula (1) (in the formula, Q represents a substituted or unsubstituted 5- to 6-membered or 9- to 10-membered heteroaryl group, R1 represents a C1-6 alkyl group) with a compound represented by formula (2) (in the formula, R2 represents a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group, a substituted or unsubstituted C3-6 cycloalkyl group, a substituted or unsubstituted phenyl group, or a substituted or unsubstituted 5- to 6-membered heteroaryl group) in the presence of a metal alkoxide or a base and a method for producing a compound represented by formula (4) (in the formula, Q, R1, and R2 represent the same as in formula (3)) that includes chemically reacting a compound represented by formula (3) with hydroxylamine or a salt thereof and dehydrating the product of the chemical reaction.
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Inventors:
KOBAYASHI SHINICHI (JP)
MATSUDA HIROKAZU (JP)
MATSUDA HIROKAZU (JP)
Application Number:
PCT/JP2022/042495
Publication Date:
May 25, 2023
Filing Date:
November 16, 2022
Export Citation:
Assignee:
NIPPON SODA CO (JP)
International Classes:
C07D401/04; C07D233/64
Domestic Patent References:
WO2020090585A1 | 2020-05-07 | |||
WO2017016910A1 | 2017-02-02 | |||
WO2017050685A1 | 2017-03-30 | |||
WO2020050212A1 | 2020-03-12 | |||
WO2020071304A1 | 2020-04-09 | |||
WO2020090585A1 | 2020-05-07 | |||
WO2018194077A1 | 2018-10-25 |
Foreign References:
JP2019065018A | 2019-04-25 |
Other References:
JEAN-FRANCUOIS MARCOUX ET AL.: "A General Preparation of Pyridines and Pyridones via the Annulation of Ketones and Esters", J. ORG. CHEM., vol. 66, no. 12, 2001, pages 4194 - 4199, XP002326844, DOI: 10.1021/jo0155198
Attorney, Agent or Firm:
MATSUNUMA Yasushi et al. (JP)
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