Title:
METHOD FOR PRODUCING ACETOIN, BUTANEDIOL, OR BUTANOL FROM ETHANOL
Document Type and Number:
WIPO Patent Application WO/2019/124782
Kind Code:
A2
Abstract:
In a method for producing acetoin, butanediol, or butanol from ethanol according to the present invention, a cell-free catalysis method was used by designing an artificial synthetic pathway so that proteins of NOX, EtDH, FLS, BDH, and DDH and mutant proteins thereof exhibit multi-step catalytic activity as enzymes. Compared to existing fermentation methods using microorganisms, the production method according to the present invention does not require cell growth and has a short synthetic pathway, a fast reaction rate, high yield and productivity, adjustment of targeted reaction conditions is convenient, and butanol can be effectively produced. Moreover, same can be reused numerous times by fixing the proteins to nanoparticles, and are also effective for producing acetoin, butanediol, or butanol, thus being economical. Therefore, the production method may be usefully adopted in the relevant industries requiring acetoin, butanediol, or butanol.
Inventors:
LEE JUNG-KUL (KR)
ZHANG LIAOYUAN (KR)
LI JING-LIN (KR)
ZHANG LIAOYUAN (KR)
LI JING-LIN (KR)
Application Number:
PCT/KR2018/014538
Publication Date:
June 27, 2019
Filing Date:
November 23, 2018
Export Citation:
Assignee:
KONKUK UNIV INDUSTRIAL COOPERATION CORPORATION (KR)
International Classes:
C12N9/00; C12N9/88; C12N11/14; C12N15/63; C12P7/16; C12P7/42
Attorney, Agent or Firm:
WIE, Byoung-Gap (KR)
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