Title:
METHOD FOR PRODUCING ACYLTHIOUREA COMPOUND
Document Type and Number:
WIPO Patent Application WO/2021/162096
Kind Code:
A1
Abstract:
The present invention relates to a method for producing 4-(2-fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide, the method comprising a step for linking 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide and 2-phenylacetyl isothiocyanate.
Inventors:
SUDA YOSHIMITSU (JP)
Application Number:
PCT/JP2021/005272
Publication Date:
August 19, 2021
Filing Date:
February 12, 2021
Export Citation:
Assignee:
TAIHO PHARMACEUTICAL CO LTD (JP)
International Classes:
C07C335/24; A61K31/47; C07D215/48
Domestic Patent References:
| WO2009125597A1 | 2009-10-15 | |||
| WO2005082855A1 | 2005-09-09 | |||
| WO2016175305A1 | 2016-11-03 | |||
| WO2009125597A1 | 2009-10-15 | |||
| WO2015046484A1 | 2015-04-02 | |||
| WO2016208744A1 | 2016-12-29 | |||
| WO2016175305A1 | 2016-11-03 | |||
| WO2018151177A1 | 2018-08-23 |
Foreign References:
| JP2020023754A | 2020-02-13 | |||
| JP2020086940A | 2020-06-04 | |||
| JP2020157815A | 2020-10-01 | |||
| JP2020157816A | 2020-10-01 |
Other References:
STEPPELER FRANZ, IWAN DOMINIKA, WOJACZYŃSKA ELŻBIETA, WOJACZYŃSKI JACEK: "Chiral Thioureas-Preparation and Significance in Asymmetric Synthesis and Medicinal Chemistry", MOLECULES, vol. 25, no. 2, 401, 18 January 2020 (2020-01-18), pages 1 - 56, XP055848074, DOI: 10.3390/molecules25020401
See also references of EP 4105200A4
See also references of EP 4105200A4
Attorney, Agent or Firm:
EIKOH PATENT FIRM, P.C. (JP)
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