Title:
METHOD FOR PRODUCING AZOLE DERIVATIVE AND INTERMEDIATE COMPOUND OF SAME
Document Type and Number:
WIPO Patent Application WO/2017/171095
Kind Code:
A1
Abstract:
Provided is a method for producing an azole derivative (I), which is reduced in the number of necessary steps. A method for producing an azole derivative (I) according to the present invention comprises: an olefination step for obtaining an olefin derivative (III) from a ketone derivative (IV); and an oxiranation step for obtaining an oxirane derivative (II) from the olefin derivative (III).
Inventors:
TOHMIYA HIRAKU (JP)
ITO ATSUSHI (JP)
KAWAYAUCHI NAOTO (JP)
NAKASHIMA KOSUKE (JP)
NAITO RYOTA (JP)
ITO ATSUSHI (JP)
KAWAYAUCHI NAOTO (JP)
NAKASHIMA KOSUKE (JP)
NAITO RYOTA (JP)
Application Number:
PCT/JP2017/013892
Publication Date:
October 05, 2017
Filing Date:
April 03, 2017
Export Citation:
Assignee:
KUREHA CORP (JP)
International Classes:
C07D249/08; C07C69/753
Domestic Patent References:
| WO2013077265A1 | 2013-05-30 | |||
| WO2012169516A1 | 2012-12-13 |
Foreign References:
| JPH0193574A | 1989-04-12 | |||
| JPH01186871A | 1989-07-26 | |||
| JPH0242003A | 1990-02-13 | |||
| JPH0578282A | 1993-03-30 | |||
| JPH05271197A | 1993-10-19 |
Other References:
COLLINS, K. D. ET AL.: "Selective Reductions of Cyclic 1,3-Diesters by Using SmI2 and H20", CHEMISTRY - A EUROPEAN JOURNAL, vol. 16, no. 33, 2010, pages 10240 - 10249, XP055430183
GUAZZELLI, G. ET AL.: "Selective Reductions of Cyclic 1,3-Diesters Using SmI2 and H20", J. AM. CHEM. SOC., vol. 131, no. 21, 2009, pages 7214 - 7215, XP055430191
RENAUD, J.-L. ET AL.: "Cobalt-mediated cycloisomerization of 5-substituted .epsilon.- acetylenic beta-keto esters construction of angular triquinane by a sequence ene/Pauson- Khand reactions", TETRAHEDRON, vol. 55, no. 16, 1999, pages 5113 - 5128, XP004161090
CORBIN, N. C. ET AL.: "Simple epoxide analogs of trichothecans", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 68, no. 12, 1979, pages 1501 - 1504, ISSN: 0022-3549
GUAZZELLI, G. ET AL.: "Selective Reductions of Cyclic 1,3-Diesters Using SmI2 and H20", J. AM. CHEM. SOC., vol. 131, no. 21, 2009, pages 7214 - 7215, XP055430191
RENAUD, J.-L. ET AL.: "Cobalt-mediated cycloisomerization of 5-substituted .epsilon.- acetylenic beta-keto esters construction of angular triquinane by a sequence ene/Pauson- Khand reactions", TETRAHEDRON, vol. 55, no. 16, 1999, pages 5113 - 5128, XP004161090
CORBIN, N. C. ET AL.: "Simple epoxide analogs of trichothecans", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 68, no. 12, 1979, pages 1501 - 1504, ISSN: 0022-3549
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
Download PDF: