Title:
METHOD FOR PRODUCING CAR-T CELLS
Document Type and Number:
WIPO Patent Application WO/2023/080178
Kind Code:
A1
Abstract:
The present invention provides a method for producing chimeric antigen receptor T (CAR-T) cells, the method comprising a step for isolating, by means of beads, T cells from a T cell supply source using a specific factor. The specific factor is CD45RA+ or the like. The method enables production of CAR-T cells having high anti-tumor activity, and enables production of highly-functional CAR-T cells easily in a short period of time at a low cost.
Inventors:
KISHIMOTO MEGUMI (JP)
SHIMIZU YUTO (JP)
KUBOTA SUSUMU (JP)
YAGYU SHIGEKI (JP)
SUEMATSU MASAYA (JP)
NAKAZAWA YOZO (JP)
TANAKA MIYUKI (JP)
SHIMIZU YUTO (JP)
KUBOTA SUSUMU (JP)
YAGYU SHIGEKI (JP)
SUEMATSU MASAYA (JP)
NAKAZAWA YOZO (JP)
TANAKA MIYUKI (JP)
Application Number:
PCT/JP2022/041076
Publication Date:
May 11, 2023
Filing Date:
November 02, 2022
Export Citation:
Assignee:
AGC INC (JP)
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
UNIV SHINSHU (JP)
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
UNIV SHINSHU (JP)
International Classes:
C12N5/0783; C12N15/11
Domestic Patent References:
| WO2020089343A1 | 2020-05-07 |
Attorney, Agent or Firm:
KAMADA, Mitsunori et al. (JP)
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